Food Safety Substance

1,2-Propylene glycol

1,2-Propylene glycol is a food additive with Approved in the EU, GRAS in the US, and data from 7 regulatory sources.

CAS 57-55-6 Indexable evidence set

FDA

GRAS

ADI / TDI

ADI 25 mg/kg bw/day

Codex

0 row(s)

SOURCE D1 identity resolution e number aliases | Food Additives | dsstox identifiers | 7 matched regulatory source group(s)

Substance Identity

Resolved identifiers used to render this food-safety record.

Substance name

1,2-Propylene glycol

CAS

57-55-6

DTXSID

DTXSID0021206

PubChem CID

1030

Evidence tier

Indexable evidence set (13)

SOURCE EU Commission EU Food Contact Materials

EU FCM Substances

EU food-contact material rows and migration-limit fields.

Jurisdiction	FCM no.	Ref no.	Substance	Use	SML	Regulation
European Union	109	23740	1,2-propanediol	additive/PPA, monomer/macromolecule	-	Regulation (EU) No 10/2011, Annex I
European Union	854	71943	perfluoro acetic acid, α-substituted with the copolymer of perfluoro-1,2-propylene glycol and perfluoro-1,1-ethylene glycol, terminated with chlorohexafluoropropyloxy groups	additive/PPA	-	Regulation (EU) No 10/2011, Annex I
European Union	109	-	1,2-propanediol	-	-	Regulation (EC) No 450/2009, Register v1.1

SOURCE JECFA JECFA ADI

JECFA ADI Values

JECFA ADI records and evaluation years.

Jurisdiction	Chemical name	JECFA no.	CAS	ADI	ADI upper	Function	Evaluation year
JECFA	PROPYLENE GLYCOL	925	57-55-6	0-25 mg/kg bw (1973)	25	CARRIER_SOLVENT, GLAZING_AGENT, HUMECTANT	2002
JECFA	1,2-PROPYLENE GLYCOL ACETATES	-	1331-12-0 (MONO-); 623-84-7 (DIACETATE)	NO ADI ALLOCATED	-	CARRIER_SOLVENT	1979

SOURCE ATSDR ATSDR MRL

ATSDR MRL Data

ATSDR minimal-risk-level rows by route and duration.

Jurisdiction	Chemical	Route	Duration	MRL	Critical effect	Status	Year
United States	PROPYLENE GLYCOL	Inhalation	Intermediate	0.009 ppm	Resp	Final	1997

SOURCE ingredients ghs classifications

Cross-Reference to Cosmetics / Chemicals / Pharma

Same-CAS public rows from adjacent Roots verticals where available.

SOURCE Cross-vertical comparison ingredients | ghs classifications

Cross-Vertical Regulatory Divergence

This substance has different regulatory treatment across food, cosmetics, and industrial use.

CosmeticsPropylene GlycolEU status: permitted Industrial / GHSDangerNITE-CMC

SOURCE FAQPage JSON-LD public food renderer rows

Frequently Asked Questions

Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.

What is 1,2-Propylene glycol used for in food?

1,2-Propylene glycol appears in food-use rows as: Preservative/Humectant.

Is 1,2-Propylene glycol safe?

This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: ADI 25 mg/kg bw/day. EU status evidence: Approved. US/FDA evidence: GRAS.

What is the ADI for 1,2-Propylene glycol?

1,2-Propylene glycol has this ADI/reference value in the food-safety tables: ADI 25 mg/kg bw/day. Source: food_substances.

Is 1,2-Propylene glycol also used in cosmetics?

1,2-Propylene glycol has a same-CAS cosmetics cross-reference: Propylene Glycol, EU status permitted.