Food Safety Substance
Glucose oxidase
Glucose oxidase is a food additive with Approved in the EU, FDA has no questions in the US, and data from 6 regulatory sources.
CAS 9001-37-0
Indexable evidence set
FDA
FDA has no questions
ADI / TDI
JECFA ADI DECISION POSTPONED
Codex
1 row(s)
SOURCE
D1 identity resolution
e number aliases | Food Additives | dsstox identifiers | 6 matched regulatory source group(s)
Substance Identity
Resolved identifiers used to render this food-safety record.
Substance name
Glucose oxidase
CAS
9001-37-0
DTXSID
DTXSID201010878
PubChem CID
64689
Evidence tier
Indexable evidence set (10)
SOURCE
EU Commission
FDA | Health Canada | Codex Alimentarius
Multi-Jurisdiction Comparison
Side-by-side status rows for the same resolved substance across public food regulators.
| Jurisdiction | Authority | Status | Evidence |
|---|---|---|---|
| European Union | EU Commission | Approved | - |
| United States | FDA | FDA has no questions | GRAS notice |
| Canada | Health Canada | Listed | Food enzyme |
| Codex | Codex Alimentarius | Listed | Antioxidant |
SOURCE
Codex Alimentarius
Codex GSFA
Codex GSFA Status
Codex Alimentarius GSFA permissions and maximum-use rows.
| Jurisdiction | INS / E-number | Function | Food category | Max level | Notes |
|---|---|---|---|---|---|
| Codex | 1102 | Antioxidant | Table 3 Foods in General (GMP) | GMP | Table 3 additive - GMP in foods in general |
SOURCE
FDA
FDA GRAS
FDA GRAS Status
US FDA GRAS notice evidence from enriched and notice tables.
| Jurisdiction | GRN | Substance | FDA response | Intended use | Basis | Notifier |
|---|---|---|---|---|---|---|
| United States | 89 | Five enzyme preparations from Aspergillus niger: Carbohydrase enzyme preparation, catalase enzyme preparation, glucose oxidase enzyme preparation, pectinase enzyme preparation, and protease enzyme preparation | FDA has no questions | Use in foods in general as an enzyme in accordance with current good manufacturing practices | Common use in food | Enzyme Technical Association |
| United States | 106 | Glucose oxidase enzyme preparation from Aspergillus oryzae carrying a gene encoding a glucose oxidase from Aspergillus niger | FDA has no questions | Use as an enzyme in baking applications and (in combination with a catalyze enzyme preparation) in the manufacture of foods such as cheese, beer, carbonated beverages, and fruit... | Scientific procedures | Novozymes North America, Inc. |
| United States | 509 | Glucose oxidase enzyme preparation derived from Penicillium chrysogenum | FDA has no questions | For use as an enzyme in various foods and powdered, dried eggs up to 30 mg TOS per kg food | Scientific Procedures | Shin Nihon Chemical Co., Ltd. |
| United States | 707 | Glucose oxidase from Penicillium produced in Trichoderma reesei | FDA has no questions | For use in baking processes at the minimum amount necessary to achieve the intended technical effect. | Scientific procedures | AB Enzymes GmbH |
| United States | 1054 | Glucose oxidase enzyme preparation produced by Aspergillus niger expressing the gene encoding glucose oxidase from A. niger | FDA has no questions | Intended for use as an enzyme at up to 7.72 mg Total Organic Solids (TOS)/kg raw material, in baking, and processing of cheese, de-sugared eggs, mayonnaise, and salad dressing. | Scientific procedures | Danisco US Inc. (A Wholly Owned-Subsidiary of International Flavors & Fragrances) |
| United States | 1071 | Glucose oxidase enzyme preparation produced by Saccharomyces cerevisiae expressing a gene encoding a glucose oxidase from Aspergillus niger | FDA has no questions | Intended for use as an enzyme at up to 30.4 mg Total Organic Solids/kg flour in the manufacture of baked goods. | Scientific procedures | Lallemand Inc. |
| United States | 1290 | Glucose oxidase enzyme preparation produced by Komagataella phaffii expressing a gene encoding glucose oxidase from Aspergillus niger | Pending | Intended for use as an enzyme in the production of baked goods at up to 18.2 mg Total Organic Solids (TOS)/kg flour. | Scientific procedures | Lallemand Inc. |
| United States | 89 | Five enzyme preparations from <i>Aspergillus niger</i>: Carbohydrase enzyme preparation, catalase enzyme preparation, glucose oxidase enzyme preparation, pectinase enzyme preparation, and protease enzyme preparation | FDA has no questions | Use in foods in general as an enzyme in accordance with current good manufacturing practices | Common use in food | Enzyme Technical Association |
| United States | 106 | Glucose oxidase enzyme preparation from <i>Aspergillus oryzae</i> carrying a gene encoding a glucose oxidase from <i>Aspergillus niger</i> | FDA has no questions | Use as an enzyme in baking applications and (in combination with a catalyze enzyme preparation) in the manufacture of foods such as cheese, beer, carbonated beverages, and fruit... | Scientific procedures | Novozymes North America, Inc. |
| United States | 509 | Glucose oxidase enzyme preparation derived from <i>Penicillium chrysogenum</i> | FDA has no questions | For use as an enzyme in various foods and powdered, dried eggs up to 30 mg TOS per kg food | Scientific Procedures | Shin Nihon Chemical Co., Ltd. |
| United States | 707 | Glucose oxidase from Penicillium produced in <I>Trichoderma reesei</I> | FDA has no questions (in PDF) | For use in baking processes at the minimum amount necessary to achieve the intended technical effect. | Scientific procedures | AB Enzymes GmbH |
| United States | 1054 | Glucose oxidase enzyme preparation produced by <i>Aspergillus niger</i> expressing the gene encoding glucose oxidase from <i>A. niger</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 7.72 mg Total Organic Solids (TOS)/kg raw material, in baking, and processing of cheese, de-sugared eggs, mayonnaise, and salad dressing. | Scientific procedures | Danisco US Inc. (A Wholly Owned-Subsidiary of International Flavors & Fragrances) |
| United States | 1071 | Glucose oxidase enzyme preparation produced by <i>Saccharomyces cerevisiae</i> expressing a gene encoding a glucose oxidase from <i>Aspergillus niger</i> | FDA has no questions (in PDF) | Intended for use as an enzyme at up to 30.4 mg Total Organic Solids/kg flour in the manufacture of baked goods. | Scientific procedures | Lallemand Inc. |
| United States | 1290 | Glucose oxidase enzyme preparation produced by <i>Komagataella phaffii</i> expressing a gene encoding glucose oxidase from <i>Aspergillus niger</i> | Pending | Intended for use as an enzyme in the production of baked goods at up to 18.2 mg Total Organic Solids (TOS)/kg flour. | Scientific procedures | Lallemand Inc. |
SOURCE
Health Canada
Health Canada Status
Health Canada food-additive permissions by functional class and food scope.
| Jurisdiction | Class | Permitted foods | Maximum level | List |
|---|---|---|---|---|
| Canada | Food enzyme | (a) Bread; White flour; Whole wheat flour | (a) Good manufacturing practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (b) Liquid egg-white, liquid whole egg or liquid yolk, destined for drying and treated with catalase as set out in item C.3 of this list | (b) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (c) Soft drinks | (c) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (d) Unstandardized bakery products | (d) Good manufacturing practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (a) Bread; White flour; Whole wheat flour | (a) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (b) Pasta | (b) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (c) Shredded cheddar cheese; Shredded (naming the variety) cheese | (c) Good Manufacturing Practice. To be applied to the surface of the cheese. | List of Permitted Food Enzymes |
| Canada | Food enzyme | (d) Unstandardized bakery products | (d) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (a) Bread; White flour; Whole wheat flour | (a) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (b) Unstandardized bakery products | (b) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (a) Bread; White flour; Whole wheat flour | (a) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (b) Liquid egg-white, liquid whole egg or liquid yolk, destined for drying and treated with catalase as set out in item C.3 of this list | (b) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (c) Pasta | (c) Good Manufacturing Practice | List of Permitted Food Enzymes |
| Canada | Food enzyme | (d) Unstandardized bakery products | (d) Good Manufacturing Practice | List of Permitted Food Enzymes |
SOURCE
JECFA
JECFA ADI
JECFA ADI Values
JECFA ADI records and evaluation years.
| Jurisdiction | Chemical name | JECFA no. | CAS | ADI | ADI upper | Function | Evaluation year |
|---|---|---|---|---|---|---|---|
| JECFA | GLUCOSE OXIDASE from PENICILLIUM AMAGASAKIENSE | - | 9001-37-0 (Glucose oxidase) | DECISION POSTPONED | - | ENZYME_PREPARATION | 1971 |
| JECFA | ASPERGILLUS NIGER, VAR. GLUCOSE OXIDASE | - | - | no_data | - | - | 1974 |
| JECFA | GLUCOSE OXIDASE from ASPERGILLUS NIGER, VAR. | - | 9001-37-0 (Glucose oxidase) | NOT SPECIFIED | - | ENZYME_PREPARATION | 1974 |
| JECFA | PENICILLIUM AMAGASAKIENSE GLUCOSE OXIDASE | - | - | no_data | - | - | 1971 |
SOURCE
ingredients
ghs classifications
Cross-Reference to Cosmetics / Chemicals / Pharma
Same-CAS public rows from adjacent Roots verticals where available.
SOURCE
Cross-vertical comparison
ingredients | ghs classifications
Cross-Vertical Regulatory Divergence
This substance has different regulatory treatment across food, cosmetics, and industrial use.
SOURCE
FAQPage JSON-LD
public food renderer rows
Frequently Asked Questions
Food-use, safety, ADI, and cross-vertical answers mirrored into FAQPage JSON-LD.
What is Glucose oxidase used for in food?
Glucose oxidase appears in food-use rows as: Preservative/Antioxidant; Antioxidant; Food enzyme.
Is Glucose oxidase safe?
This page does not assign a standalone safety verdict; it renders public regulatory evidence. ADI/reference value: JECFA ADI DECISION POSTPONED. EU status evidence: Approved. US/FDA evidence: FDA has no questions.
What is the ADI for Glucose oxidase?
Glucose oxidase has this ADI/reference value in the food-safety tables: JECFA ADI DECISION POSTPONED. Source: JECFA 1971.
Is Glucose oxidase also used in cosmetics?
Glucose oxidase has a same-CAS cosmetics cross-reference: Glucose Oxidase, EU status permitted.