Is Glucose Oxidase safe in cosmetics?
Glucose Oxidase has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Glucose Oxidase
INCI: GLUCOSE OXIDASE
Glucose Oxidase (CAS 9001-37-0) is a cosmetic cosmetic ingredient functioning as Light Stabilizer; Antimicrobial (in situ H2O2 generation). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 9001-37-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Glucose Oxidase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Light Stabilizer; Antimicrobial (in situ H2O2 generation)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
InChIKey
WQZGKKKJIJFFOK-VFUOTHLCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS status as food enzyme under FDA regulations; no specific FDA cosmetic restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glucose Oxidase.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Stabilizing agent
Regulatory List Membership (1)
EU Restricted for Children (Cosmetics)
Expert Verdict
Expert safety assessment and concern-level summary for Glucose Oxidase.
Regulatory Flags
enzyme
high-molecular-weight
in-situ-h2o2
self-preserving
gras-food
no-cir-report
no-sccs-opinion
respiratory-sensitizer-occupational
mala-s-12-homology
oral-hygiene
eu_children_restricted
Chemical Function
Stabilizing agent
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
children; Europe; Personal care
children; Europe; Personal care - dental care - toothpaste
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Glucose oxidase
Food Category
preservative
Frequently Asked Questions
Is Glucose Oxidase allowed in the EU?
Glucose Oxidase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glucose Oxidase do in cosmetics?
Glucose Oxidase functions as: Light Stabilizer; Antimicrobial (in situ H2O2 generation). It is classified as a cosmetic ingredient in our database. CAS number: 9001-37-0.
Is Glucose Oxidase used outside cosmetics?
Glucose Oxidase also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Glucose Oxidase have different safety status in cosmetics vs industrial chemicals?
Glucose Oxidase is classified GHS Danger (H334) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Glucose Oxidase compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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