1,4-Cyclohexanedicarboxylic Acid
INCI: 1,4-CYCLOHEXANEDICARBOXYLIC ACID
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for 1,4-Cyclohexanedicarboxylic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 249 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| LOAEL | 885 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
Limited cosmetic-specific toxicological dataset; used primarily in polymer chemistry rather than as a standalone cosmetic active.
Frequently Asked Questions
Is 1,4-Cyclohexanedicarboxylic Acid safe in cosmetics?
Limited cosmetic-specific toxicological dataset; used primarily in polymer chemistry rather than as a standalone cosmetic active. The EU classifies 1,4-Cyclohexanedicarboxylic Acid as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is 1,4-Cyclohexanedicarboxylic Acid allowed in the EU?
1,4-Cyclohexanedicarboxylic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 1,4-Cyclohexanedicarboxylic Acid do in cosmetics?
1,4-Cyclohexanedicarboxylic Acid functions as: Chelating agent. It is classified as a cosmetic ingredient in our database. CAS number: 1076-97-7.
What is the Margin of Safety for 1,4-Cyclohexanedicarboxylic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 1,4-Cyclohexanedicarboxylic Acid?
The NOAEL (No Observed Adverse Effect Level) for 1,4-Cyclohexanedicarboxylic Acid is 249 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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