NOAEL Studies Cosmetic Ingredient

2-Amino-4-Hydroxyethylaminoanisole NOAEL Studies

INCI: 2-AMINO-4-HYDROXYETHYLAMINOANISOLE

CAS: 83763-47-7

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.23 mg/kg rat oral 15-week dermal absorption p.28
SCCS Opinion NOAEL =15 mg/kg bw rat oral subchronic repeated dose toxicity p.18
SCCS Opinion NOAEL =15 mg/kg rat oral 15-week dermal absorption p.28
SCCS Opinion NOAEL =15 mg/kg bw/day rat oral subchronic repeated dose toxicity p.20
SCCS Opinion NOAEL =30 mg/kg bw rat - - NOAEL study p.26
SCCS Opinion NOAEL =30 mg/kg bw/day rat - - NOAEL study p.27
SCCS Opinion NOAEL =150 mg/kg bw rat - - NOAEL study p.26
SCCS Opinion NOAEL =150 mg/kg bw/day rat - - NOAEL study p.27
Regulatory source 11 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 30 mg/kg bw rat - - - p.26
Regulatory source - 30 mg/kg bw/day rat - - - p.27
Regulatory source - 150 mg/kg bw rat - - - p.26
Regulatory source - 150 mg/kg bw/day rat - - - p.27
Regulatory source - 150 mg/kg bw/day human - - - p.27
Regulatory source dermal absorption =0.23 mg/kg rat oral 15-week dermal absorption p.28
Regulatory source dermal absorption =15 mg/kg rat oral 15-week dermal absorption p.28
Regulatory source repeated dose toxicity 15 mg/kg bw rat oral subchronic repeated dose toxicity p.18
Regulatory source repeated dose toxicity 15 mg/kg bw rat dermal 15 week repeated dose toxicity p.29
Regulatory source repeated dose toxicity 15 mg/kg bw/day rat oral subchronic repeated dose toxicity p.20
Regulatory source repeated dose toxicity 15 mg/kg bw/day rat dermal 15 week repeated dose toxicity p.29
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 0NK0KYZ30R UNII - - - chemical -