NOAEL Studies Cosmetic Ingredient

3-Amino-2,4-Dichlorophenol NOAEL Studies

INCI: 3-AMINO-2,4-DICHLOROPHENOL

CAS: 61693-42-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 7 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.41 mg/kg rat oral 90 day dermal absorption p.20
SCCS Opinion NOAEL =0.74 mg/kg rat oral 90 day dermal absorption p.20
SCCS Opinion NOAEL =80 mg/kg bw rat oral 90 day dermal absorption p.20
SCCS Opinion NOAEL =80 mg/kg bw/d rat dermal 90 days dermal absorption p.21
SCCS Opinion NOAEL =115 mg/kg bw/d human - - NOAEL study p.20
SCCS Opinion NOAEL =480 mg/kg bw/d rat - 90 days genotoxicity p.15
SCCS Opinion NOAEL =2000 mg/kg bw rat - 90 days irritation p.21
Regulatory source 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 115 mg/kg bw/d human - - - p.20
Regulatory source - 115 mg/kg bw/d - - - - p.19
Regulatory source dermal absorption =0.41 mg/kg rat oral 90 day dermal absorption p.20
Regulatory source dermal absorption =0.74 mg/kg rat oral 90 day dermal absorption p.20
Regulatory source dermal absorption =80 mg/kg bw rat oral 90 day dermal absorption p.20
Regulatory source dermal absorption 80 mg/kg bw/d rat dermal 90 days dermal absorption p.21
Regulatory source genotoxicity 480 mg/kg bw/d rat - 90 days genotoxicity p.15
Regulatory source irritation 2000 mg/kg bw rat - 90 days irritation p.21
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 551I6ZAE4Q UNII - - - chemical -