NOAEL Studies Cosmetic Ingredient

3-Amino-2,6-Dimethylphenol NOAEL Studies

INCI: 3-AMINO-2,6-DIMETHYLPHENOL

CAS: 6994-64-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.08 mg/kg bw rat dermal prenatal developmental toxicity p.34
SCCS Opinion NOAEL =60 mg/kg bw/d rat dermal prenatal developmental toxicity p.34
SCCS Opinion NOAEL =60 mg/kg bw/day rat oral 14 days reproductive toxicity p.34
SCCS Opinion NOAEL =70 mg/kg bw/day rat - Chronic genotoxicity Ref.: 46, 47 3, p.21
SCCS Opinion NOAEL =150 mg/kg bw/day - - - NOAEL study p.26
SCCS Opinion NOAEL =2000 mg/kg bw rat oral 14 days reproductive toxicity p.34
Regulatory source 9 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 150 mg/kg bw/day - - - - p.26
Regulatory source - 150 mg/kg bw/day human - - - p.27
Regulatory source developmental toxicity =0.08 mg/kg bw rat dermal prenatal developmental toxicity p.34
Regulatory source developmental toxicity =60 mg/kg bw/d rat dermal prenatal developmental toxicity p.34
Regulatory source developmental toxicity =60 mg/kg bw/d rat oral prenatal developmental toxicity p.34
Regulatory source genotoxicity 70 mg/kg bw/day rat - Chronic genotoxicity p.21
Regulatory source reproductive toxicity 60 mg/kg bw/day rat oral 14 days reproductive toxicity p.34
Regulatory source reproductive toxicity 70 mg/kg bw/day rat oral 14 days reproductive toxicity p.34
Regulatory source reproductive toxicity 2000 mg/kg bw rat oral 14 days reproductive toxicity p.34
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier KK52J0MQ7D UNII - - - chemical -