NOAEL Studies Cosmetic Ingredient

3-Benzylidene Camphor NOAEL Studies

INCI: 3-BENZYLIDENE CAMPHOR

CAS: 15087-24-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 12 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =0.21 mg/kg bw rat oral - NOAEL study p.24
SCCS Opinion NOAEL =2 % rat - - NOAEL study p.24
SCCS Opinion NOAEL =7.5 mg/kg bw/d rat oral - NOAEL study p.24
SCCS Opinion NOAEL =15 mg/kg bw/day mouse oral 56 day NOAEL study p.15
SCCS Opinion NOAEL =15 mg/kg bw/d rat oral - NOAEL study p.24
SCCS Opinion NOAEL =18 - human dermal - NOAEL study p.5
SCCS Opinion NOAEL =20 mg/kg bw/day rat oral 6 week reproductive toxicity p.25
SCCS Opinion NOAEL =25 mg/kg bw/d guinea pig oral 15 days NOAEL study p.12
SCCS Opinion NOAEL =40 mg/kg bw/day - - 38 weeks genotoxicity p.13
SCCS Opinion NOAEL =50 mg/kg bw/day - - 45 d NOAEL study p.15
SCCS Opinion NOAEL =50 % rat oral - NOAEL study p.24
SCCS Opinion NOAEL =250 mg/kg bw/d rat oral sub-chronic repeated dose toxicity p.11
Regulatory source 14 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - =0.21 mg/kg bw rat oral - - p.24
Regulatory source - =2 % rat - - - p.24
Regulatory source - 2 % rat oral 4 week - p.26
Regulatory source - =7.5 mg/kg bw/d rat oral - - p.24
Regulatory source - 15 mg/kg bw/day mouse oral 56 day - p.15
Regulatory source - =15 mg/kg bw/d rat oral - - p.24
Regulatory source - 18 - human dermal - - p.5
Regulatory source - 25 mg/kg bw/d guinea pig oral 15 days - p.12
Regulatory source - 50 mg/kg bw/day - - 45 d - p.15
Regulatory source - 50 % rat oral - - p.24
Regulatory source genotoxicity 40 mg/kg bw/day - - 38 weeks genotoxicity p.13
Regulatory source repeated dose toxicity 250 mg/kg bw/d rat oral sub-chronic repeated dose toxicity p.11
Regulatory source reproductive toxicity 15 mg/kg bw/day rat - - reproductive toxicity p.25
Regulatory source reproductive toxicity 20 mg/kg bw/day rat oral 6 week reproductive toxicity p.25
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 2F60H204CM UNII - - - chemical -