Is 3-Benzylidene Camphor safe in cosmetics?
3-Benzylidene Camphor has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
3-Benzylidene Camphor
Also known as: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-3-(phenylmethylene)-, 2-Bornanone, 3-benzylidene-, 1,7,7-Trimethyl-3-(phenylmethylene)bicyclo[2.2.1]heptan-2-one, 3-Benzylidenecamphor, Benzylidenecamphor (+7 more)
INCI: 3-BENZYLIDENE CAMPHOR
3-Benzylidene Camphor (CAS 15087-24-8) is a cosmetic cosmetic ingredient functioning as UV filter (former — no longer authorized). Reported NOAEL =0.21 mg/kg bw in rat (SCCS_vision_codex); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 15087-24-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
3-Benzylidene Camphor is prohibited in EU cosmetics but has active industrial GHS classifications (H361).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
UV filter (former — no longer authorized)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
3-benzylidene-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
InChIKey
OIQXFRANQVWXJF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not an approved OTC sunscreen active ingredient (sunscreens regulated as OTC drugs)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 3-Benzylidene Camphor.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for 3-Benzylidene Camphor. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.21 mg/kg bw | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =0.21 mg/kg bw | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =0.21 mg/kg bw | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =0.21 mg/kg bw | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =7.5 mg/kg bw/d | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =7.5 mg/kg bw/d | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =7.5 mg/kg bw/d | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =7.5 mg/kg bw/d | oral | rat | NOAEL study | SCCS_vision_codex |
| NOAEL | =15 mg/kg bw/day | oral | mouse | NOAEL study | SCCS_vision_codex |
| NOAEL | =15 mg/kg bw/d | oral | rat | NOAEL study | SCCS_vision_codex |
Endocrine Disruptor Evidence (Expanded)
Cross-referenced EDC classifications, mechanism data, and dose-response evidence from EDLists, SIN List, and cosmetic-specific detail sources.
Confirmed
Evidence: High
(2019)
Health effects: No
Affected pathways: Estrogenic (ER agonist)
Regulatory framework: REACH
Source list: I
Cosmetic-Specific Mechanism
Category: UV filter
Receptor targets: ERα, AR, PR
LOEC: 1 µM
EU status: banned (Annex II)
antagonist (ER, AR, PR)
Dose-Response Data Points
| Endpoint | Target | Value | Direction |
|---|---|---|---|
| EC50_ER | ERα | 0.68 µM | agonist |
| Luciferase ERE transcription | ERa | EC50/IC50: ~0.5-1 uM; LOEC: 0.1 uM; NOEC: 0.01 uM mixed | agonist |
| AR/PR-mediated transcription (antagonist) | AR; PR | EC50/IC50: IC50 ~1-3 uM (AR); IC50 ~0.1-1 uM (PR); LOEC: 0.1 uM (PR); NOEC: 0.01 uM mixed | antagonist |
SIN List ED: Endocrine Disruptor
Cosmetic relevance: direct
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Substance of Very High Concern (SVHC)
Included: 15-Jan-2019
Endocrine disrupting properties (Article 57(f) - environment)
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1379
(EU) 2015/1298
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1379
BRIN Brazil/India Cosmetics
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (3)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| CN | banned | - | - |
| IN | permitted_uv_filter | 2.0 | sunscreen and other cosmetic products |
| BR | permitted_uv_filter | 2 | Sunscreen products; BANNED in EU |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
UV stabilizer
Regulatory List Membership (3)
EU Banned in Cosmetics
IFRA Fragrance Transparency List
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 3-Benzylidene Camphor.
Regulatory Flags
endocrine_disruptor
eu_banned_cosmetics
ifra_fragrance
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to 3-Benzylidene Camphor by CAS number or substance name.
Studies
36
Lowest NOAEL
0.21
Highest NOAEL
250
Units vary across source rows: mg/kg bw/d, mg/kg bw/day, mg/kg bw
SCCS_vision_codex
Known Synonyms
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-3-(phenylmethylene)-
2-Bornanone, 3-benzylidene-
1,7,7-Trimethyl-3-(phenylmethylene)bicyclo[2.2.1]heptan-2-one
3-Benzylidenecamphor
Benzylidenecamphor
Eusolex 6900
Ultracyd
Ultren BK
Unisol S 22
BICYCLO[2.2.1]HEPTAN-2-ONE, 1,7,7-TRIMETHYL-3- (PHENYLMETHYLENE)-
1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one-3-benzylidene
EINECS No.: 239-139-9
Chemical Function
UV stabilizer
Fragrance
Regulatory Lists
IFRA Transparency
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 3-Benzylidene Camphor allowed in the EU?
3-Benzylidene Camphor EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 3-Benzylidene Camphor do in cosmetics?
3-Benzylidene Camphor functions as: UV filter (former — no longer authorized). It is classified as a cosmetic ingredient in our database. CAS number: 15087-24-8.
What is the NOAEL for 3-Benzylidene Camphor?
The NOAEL (No Observed Adverse Effect Level) for 3-Benzylidene Camphor is =0.21 mg/kg bw based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS_vision_codex.
Is 3-Benzylidene Camphor used outside cosmetics?
3-Benzylidene Camphor also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 3-Benzylidene Camphor have different safety status in cosmetics vs industrial chemicals?
3-Benzylidene Camphor is prohibited in EU cosmetics but has active industrial GHS classifications (H361).
Compliance Tools
Check 3-Benzylidene Camphor compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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