NOAEL Studies Cosmetic Ingredient

4-METHYLPENTAN-2-OL NOAEL Studies

CAS: 108-11-2

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_inhalation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 >16 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1502; Record_ID=acute_inhalation_2935; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID2026781; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=16; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/16189/7/3/3/?documentUUID=9ab895fc-3a62-438d-95e1-e1c8cf3e15b0; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2026781
NTP_ICE_acute_oral 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =2600 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM Hazardous Substances Data Bank (undated); record_id=acute_oral_703; row=4205; data_type=In Vivo; mixture=Chemical; chemical_name=4-Methyl-2-pentanol; preferred_name=4-Methyl-2-pentanol; dtxsid=DTXSID2026781; url=https://pubchem.ncbi.nlm.nih.gov/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2026781; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 =2590 mg/kg bw Rat oral acute Rat Acute Oral Toxicity NLM ChemIDplus TEST (undated); record_id=acute_oral_702; row=4206; data_type=In Vivo; mixture=Chemical; chemical_name=4-Methyl-2-pentanol; preferred_name=4-Methyl-2-pentanol; dtxsid=DTXSID2026781; url=https://chem.nlm.nih.gov/chemidplus/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2026781; source_file=acute_oral.xlsx
NTP_ICE_endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=3978; RecordID=ARPathway2016_504; DatasetName=ARPathway2016; DTXSID=DTXSID2026781; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID2026781
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =83 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15633455_15633456:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9fbd6d4119bf1a4ca4ebda9117d84150
ToxValDB_RSL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_RSL RfC =3 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759b87ce4b0a7c65d37b4e2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.epa.gov/risk/regional-screening-levels-rsls-generic-tables; STUDY_GROUP=RSL:15657288:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c9a06182a4296c2d0ec4d21893d0fc36
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 8U34XJK0R0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"8U34XJK0R0"}
openFDA substances FDA UNII substance identifier 8U34XJK0R0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"8U34XJK0R0"}
openFDA substances FDA UNII substance identifier 8U34XJK0R0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"8U34XJK0R0"}
openFDA substances FDA UNII substance identifier 8U34XJK0R0 UNII - - - chemical {"approval_status":null,"molecular_formula":"C6H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"8U34XJK0R0"}