Good Cosmetic Ingredient NOAEL Data GHS Classified

4-METHYLPENTAN-2-OL

CAS Number

108-11-2

Function

Perfuming

Safety Rating

GOOD

Regulatory Status

🇪🇺 EU Status Permitted

🇺🇸 US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for 4-METHYLPENTAN-2-OL. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint	Value	Route	Species	Study Type	Source
NOAEL	30 mg/kg bw/day	oral	rat	oral	REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects

The substance is irritating to the eyes, skin and respiratory tract. Exposure could cause lowering of consciousness.

Long-term Exposure Effects

The substance defats the skin, which may cause dryness or cracking.

Routes of Exposure

The substance can be absorbed into the body by inhalation of its vapour and through the skin.

Expert Verdict

4-METHYLPENTAN-2-OL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted fragrance needs-enrichment ifra_fragrance

Frequently Asked Questions

Is 4-METHYLPENTAN-2-OL safe in cosmetics?

4-METHYLPENTAN-2-OL is listed in the EU CosIng database with functions: Perfuming It is permitted in the EU without specific restrictions. The EU classifies 4-METHYLPENTAN-2-OL as "Permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is 4-METHYLPENTAN-2-OL allowed in the EU?

4-METHYLPENTAN-2-OL EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-METHYLPENTAN-2-OL do in cosmetics?

4-METHYLPENTAN-2-OL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 108-11-2.

What is the NOAEL for 4-METHYLPENTAN-2-OL?

The NOAEL (No Observed Adverse Effect Level) for 4-METHYLPENTAN-2-OL is 30 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

Compliance Tools

Check 4-METHYLPENTAN-2-OL compliance across multiple jurisdictions:

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Ingredient Decoder

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82 Allergen Checker

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Substance Compliance

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MoS Calculator

Calculate Margin of Safety using SCCS methodology

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Heavy Metal Limits

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