NOAEL Studies Cosmetic Ingredient

6-Amino-M-Cresol NOAEL Studies

INCI: 6-AMINO-M-CRESOL

CAS: 2835-98-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =50 mg/kg bw/d rat oral Sub-chronic repeated dose toxicity p.16
SCCS Opinion NOAEL =200 mg/kg bw/d - - - NOAEL study p.25
SCCS Opinion NOAEL =500 mg/kg bw/d rat - Chronic genotoxicity p.16
Regulatory source 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 200 mg/kg bw/d - - - - p.25
Regulatory source genotoxicity 500 mg/kg bw/d rat - Chronic genotoxicity p.16
Regulatory source repeated dose toxicity 50 mg/kg bw/d rat oral Sub-chronic repeated dose toxicity p.16
Regulatory source repeated dose toxicity 50 mg/kg bw/d rat oral 28 days repeated dose toxicity p.36
Regulatory source repeated dose toxicity 200 mg/kg bw/d rat - subchronic repeated dose toxicity p.36
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier QCG4ES2A26 UNII - - - chemical -