Abietic Acid

Also known as: 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aR,4bR,10aR)-, (-)-Abietic acid, 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6, 10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1α,4aβ,4bα,10aα)], 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1α,4aβ,4bα,10aα)]-, 7,13-Abietadien-18-oic acid (+15 more)

INCI: ABIETIC ACID

Abietic Acid (CAS 514-10-3) is a cosmetic cosmetic ingredient functioning as Surfactant, emulsifying agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 514-10-3 →

Auto-generated CPSR Part A draft with source citations
Function
Surfactant, emulsifying agent
Safety Rating
MODERATE

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes No specific FDA restriction; CIR has reviewed rosin and colophony derivatives

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Abietic Acid.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization AOP Dashboard

Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.

DPRA Cys %
99.9%
DPRA Lys %
16.1%
KeratinoSens IC50
104.61 µM
hCLAT CV75
89.6 µg/mL
LLNA EC3
15%
NESIL
3750 µg/cm²
LLNA: Weak (1B) GHS: 1B

Source: LLNA: Gerberick et al. (2005); DPRA: Natsch et al. 2013 [DOI:10.1002/jat.2868] | Nukada et al. 2013 [DOI:10.1016/j.tiv.2012.11.006]; KS: Emter et al. 2010 [DOI:10.1016/j.taap.2010.03.009]; hCLAT: Ashikaga et al. 2010 [DOI:10.1177/026119291003800403]

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Emulsifier Fragrance Surfactant (surface active agent)
Regulatory List Membership (2)
FDA Indirect Food Contact Additives Consumer Product Chemical

Expert Verdict

Expert safety assessment and concern-level summary for Abietic Acid.

Regulatory Flags

potential-allergen

Known Synonyms

1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aR,4bR,10aR)- (-)-Abietic acid 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6, 10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1α,4aβ,4bα,10aα)] 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,4b,5,6,10,10a-decahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1α,4aβ,4bα,10aα)]- 7,13-Abietadien-18-oic acid Abietic acid, (-)- l-Abietic acid Podocarpa-7,13-dien-15-oic acid, 13-isopropyl- (1R,4aR,4bR,10aR)-1,2,3,4,4a,4b,5,6,10,10a-Decahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid Abieta-7,13-diene-18-oic acid NSC 25149 Odomit B 10 Sylvic acid Abietate EINECS 208-178-3 13-Isopropylpodocarpa-7,13-dien-15-oic acid Kyselina abietova UNII-V3DHX33184 ZAO ZAO (natural product)

Chemical Function

Surfactant (surface active agent) Emulsifier Fragrance

Regulatory Lists

CEDI Indirect additives food contact (10/2018) consumer_product

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
ABIETIC ACID
ChEMBL ID
CHEMBL71893
View full pharmaceutical profile →

Frequently Asked Questions

Is Abietic Acid safe in cosmetics?

Abietic Acid has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.

Is Abietic Acid allowed in the EU?

Abietic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Abietic Acid do in cosmetics?

Abietic Acid functions as: Surfactant, emulsifying agent. It is classified as a cosmetic ingredient in our database. CAS number: 514-10-3.

Is Abietic Acid used outside cosmetics?

Abietic Acid also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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