Is Acetyl Glutamine safe in cosmetics?
Acetyl Glutamine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Acetyl Glutamine
Also known as: 5-Hydroxy-N-(1-hydroxyethylidene)-5-iminonorvaline, N-Acetyl-L-glutamine, L-Glutamine, N-acetyl-
INCI: ACETYL GLUTAMINE
Acetyl Glutamine (CAS 35305-74-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent; moisture barrier support. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 35305-74-9 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent; moisture barrier support
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA restriction; CIR 2013 alpha-amino acids assessment concluded safe for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl Glutamine.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl Glutamine.
Regulatory Flags
skin-conditioning
amino-acid-derivative
humectant
barrier-support
cir-reviewed
Known Synonyms
5-Hydroxy-N-(1-hydroxyethylidene)-5-iminonorvaline
N-Acetyl-L-glutamine
L-Glutamine, N-acetyl-
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Frequently Asked Questions
Is Acetyl Glutamine allowed in the EU?
Acetyl Glutamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Glutamine do in cosmetics?
Acetyl Glutamine functions as: Skin conditioning agent; moisture barrier support. It is classified as a cosmetic ingredient in our database. CAS number: 35305-74-9.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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ACETALDEHYDE
Moderate
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Fragrance
ACETOBACTER FERMENT EXTRACT FILTRATE
Good
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Deodorant
ACETOBACTER/ASPERGILLUS/LACTOBACILLUS/LEUCONOSTOC/PEDIOCOCCUS/SACCHAROMYCES/ZYGOSACCHAROMYCES/CITRUS UNSHIU FRUIT/CITRUS JAPONICA FRUIT/CITRUS JUNOS FRUIT/ APPLE FRUIT/BANANA FRUIT/PAPAYA FRUIT/ PYRUS SEROTINA FRUIT/ DIOSPYROS KAKI FRUIT/WATERMELON FRUIT/PEACH FRUIT/ PRUNUS MUME FRUIT/FIG FRUIT/CHAENOMELES SINENSIS FRUIT/ERIOBOTRYA JAPONICA FRUIT/APRICOT FRUIT/ ZIZYPHUS JUJUBA FRUIT/CUCURBITA MAXIMA FRUIT/CASTANEA CRENATA FRUIT/VITIS COIGNETIAE FRUIT/RASPBERRY FRUIT/MOMORDICA GROSVENORII FRUIT/LYCIUM CHINENSE FRUIT/GLYCINE MAX SEED/PHASEOLUS ANGULARIS SEED/CANAVALIA ENSIFORMIS SEED/RICE SEED/HORDEUM VULGARE SEED/COIX LACRYMA-JOBI MA-YUEN SEED/ECHINOCHLOA CRUS-GALLI SEED/SETARIA ITALICA SEED/MILLET SEED/HEMEROCALLIS FULVA FLOWER/CABBAGE LEAF/STEM/MORUS BOMBYCIS LEAF/PERILLA FRUTESCENS LEAF/IPOMOEA BATATAS ROOT/COLOCASIA ANTIQUORUM TUBER/DIOSCOREA BATATAS RHIZOME/IRIDEA LAMINARIOIDES/LAMINARIA JAPONICA/NEMACYSTUS DECIPIENS/UNDARIA PINNATIFIDA/RADISH ROOT/TURNIP ROOT/CARROT ROOT/ARCTIUM LAPPA ROOT/NELUMBO NUCIFERA RHIZOME/ONION BULB/LILIUM AURATUM BULB/LICORICE ROOT/SAGITTARIA TRIFOLIA ROOT/SESAME SEED/GINKGO BILOBA SEED/JUGLANS SUBCORDIFORMIS FRUIT/PANAX GINSENG SEED/ACTINIDIA POLYGAMA FRUIT/HYDNUM ERINACEUM FRUITING BODY/GRIFOLA FRONDOSA FRUITING BODY/PRUNUS SALICINA FRUIT/AKEBIA QUINATA FRUIT/CRATAEGUS CUNEATA FRUIT/CORNUS OFFICINALIS FRUIT/NEPHELIUM LONGANA FRUIT/HOUTTUYNIA CORDATA/ARTEMISIA PRINCEPS/SASA VEITCHII LEAF/GLECHOMA HEDERACEA/CHAMOMILLA RECUTITA FLOWER/EQUISETUM ARVENSE/CASSIA OBTUSIFOLIA SEED/TARAXACUM OFFICINALE/ISODON JAPONICUS/SAFFLOWER FLOWER/PLANTAGO ASIATICA/SMALLANTHUS SONCHIFOLIUS ROOT/GARLIC BULB/GINGER RHIZOME/BEET RHIZOME/POLYGONUM ODORATUM RHIZOME/TURMERIC RHIZOME/ACANTHOPANAX SIEBOLDIANUS ROOT/PINUS KORAIENSIS SEED/LENTINUS EDODES FRUITING BODY/AURICULARIA AURICULA/VITIS LABRUSCA FRUIT/HELIANTHUS TUBEROSUS TUBER FERMENT EXTRACT
Good
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Skin Conditioning
ACETOBACTER/ASPERGILLUS/LACTOBACILLUS/LEUCONOSTOC/PEDIOCOCCUS/SACCHAROMYCES/ZYGOSACCHAROMYCES/HORDEUM VULGARE SEED/SOYBEAN SEED/RICE SEED/CANAVALIA GLADIATA SEED/PHASEOLUS ANGULARIS SEED/COIX LACHRYMA-JOBI MA-YUEN SEED/ECHINOCHLOA UTILIS SEED/SETARIA ITALICA SEED/MILLET SEED/CITRUS UNSHIU FRUIT/VITIS LABRUSCA FRUIT/APPLE FRUIT/VITIS COIGNETIAE FRUIT/MUSA SAPIENTUM FRUIT/PEACH FRUIT/DIOSPYROS KAKI FRUIT/PAPAYA FRUIT/PYRUS PYRIFOLIA FRUIT/WATERMELON FRUIT/PRUNUS MUME FRUIT/FIG FRUIT/CHAENOMELES SINENSIS FRUIT/CUCURBITA MAXIMA FRUIT/RUBUS IDAEUS FRUIT/FORTUNELLA CRASSIFOLIA FRUIT/CITRUS JUNOS FRUIT/ERIOBOTRYA JAPONICA FRUIT/APRICOT FRUIT/ZIZYPHUS JUJUBA FRUIT/CASTANEA CRENATA FRUIT/LYCIUM CHINENSE FRUIT/ACTINIDIA POLYGAMA FRUIT/PRUNUS SALICINA FRUIT/AKEBIA QUINATA FRUIT/MOMORDICA GROSVENORII FRUIT/CRATAEGUS CUNEATA FRUIT/CORNUS OFFICINALIS FRUIT/EUPHORIA LONGAN FRUIT/PANAX GINSENG FRUIT/IPOMOEA BATATAS ROOT/HELIANTHUS TUBEROSUS TUBER/CARROT ROOT/ONION BULB/BETA VULGARIS ROOT/COLOCASIA ESCULENTA TUBER/DIOSCOREA JAPONICA RHIZOME/RADISH ROOT/TURNIP ROOT/ARCTIUM LAPPA ROOT/NELUMBO NUCIFERA RHIZOME/POLYMNIA SONCHIFOLIA ROOT/LILIUM AURATUM BULB/SAGITTARIA TRIFOLIA EDULIS TUBER/GINGER RHIZOME/GARLIC BULB/GLYCYRRHIZA GLABRA ROOT/POLYGONATUM ODORATUM RHIZOME/TURMERIC RHIZOME/ACANTHOPANAX GRACILISTYLUS ROOT/CABBAGE LEAF/STEM/PERILLA OCYMOIDES LEAF/MORUS BOMBYCIS LEAF/HEMEROCALLIS FULVA KWANSO FLOWER/HOUTTUYNIA CORDATA/ARTEMISIA PRINCEPS/SASA VEITCHII LEAF/GLECHOMA HEDERACEA/MATRICARIA FLOWER/EQUISETUM ARVENSE/ISODON JAPONICUS/SAFFLOWER FLOWER/PLANTAGO ASIATICA/DANDELION/LAMINARIA JAPONICA LEAF/UNDARIA PINNATIFIDA LEAF/RHODOGLOSSUM PULCHERUM LEAF/NEMACYSTUS DECIPIENS/SESAME SEED/JUGLANS SIEBOLDIANA SEED/GINKGO BILOBA SEED/PINUS KORAIENSIS SEED/CASSIA OBTUSIFOLIA SEED/GRIFOLA FRONDOSA FRUITING BODY/HERICIUM ERINACEUM FRUITING BODY/LENTINUS EDODES FRUITING BODY/AURICULARIA AURICULA FRUITING BODY FERMENT EXTRACT
Good
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