Acetyl Methoxykynurenamine HCl

CAS Number
95245-30-0
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Endogenous melatonin metabolite (AMK) with potent antioxidant and anti-inflammatory properties; extremely limited cosmetic use history and would require a full toxicological dossier for regulatory submission.

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Concern Level: Moderate

Frequently Asked Questions

Is Acetyl Methoxykynurenamine HCl safe in cosmetics?

Endogenous melatonin metabolite (AMK) with potent antioxidant and anti-inflammatory properties; extremely limited cosmetic use history and would require a full toxicological dossier for regulatory submission. The EU classifies Acetyl Methoxykynurenamine HCl as "permitted". Safety rating: MODERATE.

Is Acetyl Methoxykynurenamine HCl allowed in the EU?

Acetyl Methoxykynurenamine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What is the Margin of Safety for Acetyl Methoxykynurenamine HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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Is Acetyl Methoxykynurenamine HCl in Your Products?

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