Acetylsalicyloyl Pentapeptide-33

INCI: ACETYLSALICYLOYL PENTAPEPTIDE-33

CAS Number
Not assigned (novel synthetic peptide conjugate)
Function
Antioxidant, skin protecting
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; governed by general cosmetic ingredient safety substantiation under 21 CFR 740.10

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains a salicylate moiety; caution in pregnancy and breastfeeding due to general salicylate avoidance guidance; patch-test recommended for aspirin-sensitive individuals.

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Concern Level: Low

Frequently Asked Questions

Is Acetylsalicyloyl Pentapeptide-33 safe in cosmetics?

Contains a salicylate moiety; caution in pregnancy and breastfeeding due to general salicylate avoidance guidance; patch-test recommended for aspirin-sensitive individuals. The EU classifies Acetylsalicyloyl Pentapeptide-33 as "permitted". Safety rating: GOOD.

Is Acetylsalicyloyl Pentapeptide-33 allowed in the EU?

Acetylsalicyloyl Pentapeptide-33 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acetylsalicyloyl Pentapeptide-33 do in cosmetics?

Acetylsalicyloyl Pentapeptide-33 functions as: Antioxidant, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (novel synthetic peptide conjugate).

What is the Margin of Safety for Acetylsalicyloyl Pentapeptide-33?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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