NOAEL Studies Cosmetic Ingredient

Acid Black 1 NOAEL Studies

INCI: ACID BLACK 1

CAS: 1064-48-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 0.300000011921 mg/kg bw/day rat oral 90 day Subchronic SCCS; Braun W.H., Damme B., Flade D., Konrad D. 13-Week Oral Toxicity (Gavage) Study inthe Rat. RCC Ltd, Study nr 851932, 29 September 2004
SCCS Opinion 5 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =1 - rat - - NOAEL study p.18
SCCS Opinion NOAEL =5 mg/kg/day - - 90-day NOAEL study p.19
SCCS Opinion NOAEL =40 mg/kg bw/day human - - developmental toxicity p.27
SCCS Opinion NOAEL =0.78 mg/kg bw/d rat oral 90-day dermal absorption p.28
SCCS Opinion NOAEL =0.5 % mouse oral 90-day dermal absorption p.32
Regulatory source 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 1 - rat - - - p.18
Regulatory source - 5 mg/kg/day - - 90-day - p.19
Regulatory source dermal absorption =0.78 mg/kg bw/d rat oral 90-day dermal absorption p.28
Regulatory source dermal absorption 0.5 % mouse oral 90-day dermal absorption p.32
Regulatory source developmental toxicity 40 mg/kg bw/day human - - developmental toxicity p.27
Regulatory source repeated dose toxicity 40 mg/kg bw/day rat dermal sub-chronic repeated dose toxicity p.29
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier SZT789770M UNII - - - chemical -