Moderate Cosmetic Ingredient NOAEL Data

Allyl Phenoxyacetate

INCI: ALLYL PHENOXYACETATE

CAS Number
7493-74-5
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically restricted by FDA; IFRA standards apply voluntarily

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Allyl Phenoxyacetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 mg/kg bw/day oral rat oral REACH

Expert Verdict

Delayed irritant potential from free allyl alcohol; ensure CoA specifies free allyl alcohol level

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive eu_cosing_listed jecfa_safe

Frequently Asked Questions

Is Allyl Phenoxyacetate safe in cosmetics?

Delayed irritant potential from free allyl alcohol; ensure CoA specifies free allyl alcohol level The EU classifies Allyl Phenoxyacetate as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Allyl Phenoxyacetate allowed in the EU?

Allyl Phenoxyacetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Allyl Phenoxyacetate do in cosmetics?

Allyl Phenoxyacetate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 7493-74-5.

What is the Margin of Safety for Allyl Phenoxyacetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Allyl Phenoxyacetate?

The NOAEL (No Observed Adverse Effect Level) for Allyl Phenoxyacetate is 50 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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