Aluminum Zirconium Trichlorohydrex Gly

INCI: ALUMINUM ZIRCONIUM TRICHLOROHYDREX GLY

CAS Number
134375-99-8
Function
Antiperspirant; contains monomeric/polymeric Zr4+ and Al3+ complexes with hydroxide, chloride, and glycine
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes FDA-approved OTC antiperspirant active

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Restricted in Canada. One study found approximately 0.012% absorption (approximately 4 µg Al from single bilateral application). Caution advised for individuals with chronic kidney disease due to reduced aluminum excretion.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Aluminum Zirconium Trichlorohydrex Gly safe in cosmetics?

Restricted in Canada. One study found approximately 0.012% absorption (approximately 4 µg Al from single bilateral application). Caution advised for individuals with chronic kidney disease due to reduced aluminum excretion. The EU classifies Aluminum Zirconium Trichlorohydrex Gly as "restricted". Safety rating: GOOD.

Is Aluminum Zirconium Trichlorohydrex Gly allowed in the EU?

Aluminum Zirconium Trichlorohydrex Gly EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aluminum Zirconium Trichlorohydrex Gly do in cosmetics?

Aluminum Zirconium Trichlorohydrex Gly functions as: Antiperspirant; contains monomeric/polymeric Zr4+ and Al3+ complexes with hydroxide, chloride, and glycine. It is classified as a cosmetic ingredient in our database. CAS number: 134375-99-8.

What is the Margin of Safety for Aluminum Zirconium Trichlorohydrex Gly?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Aluminum Zirconium Trichlorohydrex Gly in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Aluminum Zirconium Trichlorohydrex Gly in your formulation.