NOAEL Studies Cosmetic Ingredient

Ammonium Dodecylbenzenesulfonate NOAEL Studies

INCI: AMMONIUM DODECYLBENZENESULFONATE

CAS: 1331-61-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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CIR Safety Assessment 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL =0.2 % rat oral 6 months repeated dose toxicity 0; 2; 6, p.10
CIR Safety Assessment NOAEL =1 % rat oral 6 months repeated dose toxicity 0; 2; 6, p.10
CIR Safety Assessment NOAEL =100 mg/kg dog - chronic NOAEL study 10; 100; 22, p.9
ECHA 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA NOAEL =350 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaa8be4b0a7c65d1b65f6; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/24944/7/9/2?documentUUID=d84c77bf-c195-414e-a82b-b38065926996; YEAR=2005; ORIGINAL_YEAR=2005; STUDY_GROUP=ECHA IUCLID:15857918:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_eb8b7e116a781706262a3f2286a19ec8
ToxValDB GESTIS DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB GESTIS DNEL DNEL systemic =10 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629813:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_fcd9c13c28b08d9ee8bb11d1e9c03edc
Regulatory source 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 100 mg/kg dog - chronic - p.9
Regulatory source repeated dose toxicity 0.2 % rat oral 6 months repeated dose toxicity p.10
Regulatory source repeated dose toxicity 1 % rat oral 6 months repeated dose toxicity p.10