Is Ammonium Dodecylbenzenesulfonate safe in cosmetics?
Ammonium Dodecylbenzenesulfonate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 5 toxicological study endpoint(s) are available in our database.
Ammonium Dodecylbenzenesulfonate
Also known as: Atlox 4817B, Newcol 210, Dodecylbenzene ammonium sulfonate, EINECS 215-559-8
INCI: AMMONIUM DODECYLBENZENESULFONATE
Ammonium Dodecylbenzenesulfonate (CAS 1331-61-9) is a cosmetic cosmetic ingredient functioning as Cleansing, foaming, surfactant. Reported NOAEL =100 mg/kg in dog (CIR Safety Assessment); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1331-61-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ammonium Dodecylbenzenesulfonate is classified GHS Danger (H302, H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Cleansing, foaming, surfactant
Safety Rating
MODERATE
Chemistry & Identifiers
EC Number
215-559-8
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FDA permits alkylbenzenesulfonate salts as indirect food additives (emulsifiers/surface active agents); CIR reviewed dodecylbenzenesulfonate salts
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Dodecylbenzenesulfonate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Ammonium Dodecylbenzenesulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =100 mg/kg | - | dog | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg | - | dog | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg | - | dog | NOAEL study | CIR Safety Assessment |
| NOAEL | =100 mg/kg | - | dog | NOAEL study | CIR Safety Assessment |
| NOAEL | =350 mg/kg bw/day | oral | Rat | reproduction developmental | ECHA |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Cleaning agent
Foamant
Surfactant (surface active agent)
Expert Verdict
Expert safety assessment and concern-level summary for Ammonium Dodecylbenzenesulfonate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Ammonium Dodecylbenzenesulfonate by CAS number or substance name.
Studies
5
Lowest NOAEL
100
Highest NOAEL
350
Units vary across source rows: mg/kg, mg/kg bw/day
CIR Safety Assessment
ECHA
Known Synonyms
Atlox 4817B
Newcol 210
Dodecylbenzene ammonium sulfonate
EINECS 215-559-8
Chemical Function
Surfactant (surface active agent)
Cleaning agent
Foamant
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Ammonium Dodecylbenzenesulfonate allowed in the EU?
Ammonium Dodecylbenzenesulfonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Dodecylbenzenesulfonate do in cosmetics?
Ammonium Dodecylbenzenesulfonate functions as: Cleansing, foaming, surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 1331-61-9.
What is the NOAEL for Ammonium Dodecylbenzenesulfonate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Dodecylbenzenesulfonate is =100 mg/kg based on a NOAEL study study via oral route in dog. A total of 5 study endpoints are available. Source: CIR Safety Assessment.
Is Ammonium Dodecylbenzenesulfonate used outside cosmetics?
Ammonium Dodecylbenzenesulfonate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ammonium Dodecylbenzenesulfonate have different safety status in cosmetics vs industrial chemicals?
Ammonium Dodecylbenzenesulfonate is classified GHS Danger (H302, H315, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Ammonium Dodecylbenzenesulfonate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Alpha-Glucan Oligosaccharide-1
Excellent
Same category
Skin conditioning, cleansing, smoothi...
Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer
Excellent
Same category
Dispersing agent (nonsurfactant), vis...
Ammonium Cocoyl Isethionate
Excellent
Same category
Surfactant – cleansing, foaming
Ammonium Lauryl Sulfosuccinate
Excellent
Same category
Cleansing, foaming, surfactant
Ammonium Stearate
Excellent
Same category
Cleansing, surfactant, emulsifying
Apricot Kernel Oil Polyglyceryl-10 Esters
Excellent
Same category
Skin conditioning, emollient, surfact...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
AMMONIUM POLYACRYLATE
Good
Browse nearby
Film Forming, Light Stabilizer, Surfa...
AMMOPHILA ARENARIA ROOT EXTRACT
Good
Browse nearby
Skin Conditioning
AMP-ACRYLATES/C1-18 ALKYL ACRYLATE/C1-8 ALKYL ACRYLAMIDE/HYDROXYETHYLACRYLATE COPOLYMER
Moderate
Browse nearby
Hair Waving Or Straightening
Is Ammonium Dodecylbenzenesulfonate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ammonium Dodecylbenzenesulfonate in your formulation.