Apium Graveolens Root Extract

INCI: APIUM GRAVEOLENS ROOT EXTRACT

CAS Number
89997-35-3
Function
Skin Conditioning; Antioxidant; Anti-inflammatory; Antimicrobial
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR safety review completed; no FDA prohibition; GRAS status applies to celery as food; cosmetic use self-affirmed safe at typical concentrations

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe at typical cosmetic use concentrations. Root extract contains trace furanocoumarins (2.6โ€“10.2 mg/kg); phototoxicity risk is low but photosensitivity precaution warranted in leave-on products at high concentrations. Anti-inflammatory, antioxidant, and antimicrobial activity supported by recent literature. No EU or US restrictions.

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Concern Level: Low

Regulatory Flags

no-cir-review trace-furanocoumarins phototoxicity-low-risk apiaceae-cross-reactivity limited-safety-data skin-conditioning antioxidant anti-inflammatory fda_food_additive

Frequently Asked Questions

Is Apium Graveolens Root Extract safe in cosmetics?

Safe at typical cosmetic use concentrations. Root extract contains trace furanocoumarins (2.6โ€“10.2 mg/kg); phototoxicity risk is low but photosensitivity precaution warranted in leave-on products at high concentrations. Anti-inflammatory, antioxidant, and antimicrobial activity supported by recent literature. No EU or US restrictions. The EU classifies Apium Graveolens Root Extract as "permitted". Safety rating: GOOD.

Is Apium Graveolens Root Extract allowed in the EU?

Apium Graveolens Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Apium Graveolens Root Extract do in cosmetics?

Apium Graveolens Root Extract functions as: Skin Conditioning; Antioxidant; Anti-inflammatory; Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 89997-35-3.

What is the Margin of Safety for Apium Graveolens Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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