Apium Graveolens Extract

INCI: APIUM GRAVEOLENS EXTRACT

CAS Number
89997-35-3 / EC 289-668-4
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; CIR has not issued a final safety assessment specific to this extract

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phototoxicity โ€” furanocoumarins are established phototoxins (UVA-activated DNA cross-linking); must test for bergapten/psoralen content. Allergenicity โ€” celery-mugwort-birch-spice syndrome. Use only in rinse-off or low-concentration leave-on with furanocoumarin spec <1 ppm if phototoxicity is a concern

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen fda_food_additive

Frequently Asked Questions

Is Apium Graveolens Extract safe in cosmetics?

Phototoxicity โ€” furanocoumarins are established phototoxins (UVA-activated DNA cross-linking); must test for bergapten/psoralen content. Allergenicity โ€” celery-mugwort-birch-spice syndrome. Use only in rinse-off or low-concentration leave-on with furanocoumarin spec <1 ppm if phototoxicity is a concern The EU classifies Apium Graveolens Extract as "permitted". Safety rating: MODERATE.

Is Apium Graveolens Extract allowed in the EU?

Apium Graveolens Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Apium Graveolens Extract do in cosmetics?

Apium Graveolens Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 89997-35-3 / EC 289-668-4.

What is the Margin of Safety for Apium Graveolens Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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