Azadirachta Indica Leaf Extract

INCI: AZADIRACHTA INDICA LEAF EXTRACT

CAS Number
84696-25-3
Function
Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No GRAS designation required for topical cosmetic use. FDA has not flagged this ingredient. EWG VERIFIED status requires adequate substantiation due to enhanced absorption concern.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Safe for cosmetic use. Leaf extract is distinct from the prohibited kernel (seed) extract and carries no EU or US restriction. Well-documented antimicrobial, antifungal, anti-inflammatory, and antioxidant profile supports use in acne, skin conditioning, and problem-skin formulations.

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Concern Level: Low

Regulatory Flags

enhanced-skin-absorption endocrine-disruption-low ecotoxicology-low ewg-verified-restricted no-cir-assessment patch-test-recommended seed-extract-eu-banned-leaf-not

Frequently Asked Questions

Is Azadirachta Indica Leaf Extract safe in cosmetics?

Safe for cosmetic use. Leaf extract is distinct from the prohibited kernel (seed) extract and carries no EU or US restriction. Well-documented antimicrobial, antifungal, anti-inflammatory, and antioxidant profile supports use in acne, skin conditioning, and problem-skin formulations. The EU classifies Azadirachta Indica Leaf Extract as "permitted". Safety rating: GOOD.

Is Azadirachta Indica Leaf Extract allowed in the EU?

Azadirachta Indica Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Azadirachta Indica Leaf Extract do in cosmetics?

Azadirachta Indica Leaf Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3.

What is the Margin of Safety for Azadirachta Indica Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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