Azadirachta Indica Bark Extract

INCI: AZADIRACHTA INDICA BARK EXTRACT

CAS Number
84696-25-3 (general neem extract CAS)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains nimbin, nimbidin, and other bioactives with anti-inflammatory and antimicrobial properties; potential for irritation at high concentrations; traditional use is well-documented but modern safety data is limited for this specific fraction. Derived from bark of Azadirachta indica (Neem Tree) via solvent extraction; plant origin; long history of Ayurvedic use

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Azadirachta Indica Bark Extract safe in cosmetics?

Contains nimbin, nimbidin, and other bioactives with anti-inflammatory and antimicrobial properties; potential for irritation at high concentrations; traditional use is well-documented but modern safety data is limited for this specific fraction. Derived from bark of Azadirachta indica (Neem Tree) via solvent extraction; plant origin; long history of Ayurvedic use The EU classifies Azadirachta Indica Bark Extract as "permitted". Safety rating: MODERATE.

Is Azadirachta Indica Bark Extract allowed in the EU?

Azadirachta Indica Bark Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Azadirachta Indica Bark Extract do in cosmetics?

Azadirachta Indica Bark Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-25-3 (general neem extract CAS).

What is the Margin of Safety for Azadirachta Indica Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Azadirachta Indica Bark Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Azadirachta Indica Bark Extract in your formulation.