NOAEL Studies Active Ingredient

Azelaic Acid NOAEL Studies

INCI: AZELAIC ACID

CAS: 123-99-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 >5000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_1855; row=13325; data_type=In Vivo; mixture=Chemical; chemical_name=Nonanedioic acid; preferred_name=Nonanedioic acid; dtxsid=DTXSID8021640; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8021640; source_file=acute_oral.xlsx
NTP_ICE_endocrine 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=12386; RecordID=ARPathway2016_727; DatasetName=ARPathway2016; DTXSID=DTXSID8021640; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8021640
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =17.632 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629903:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0e2f778ce8ffb0d35a882a367c2e2f36
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier F2VW3D43YT UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H16O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"F2VW3D43YT"}
openFDA substances FDA UNII substance identifier F2VW3D43YT UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H16O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"F2VW3D43YT"}
openFDA substances FDA UNII substance identifier F2VW3D43YT UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H16O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"F2VW3D43YT"}
openFDA substances FDA UNII substance identifier F2VW3D43YT UNII - - - chemical {"approval_status":null,"molecular_formula":"C9H16O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"F2VW3D43YT"}