NOAEL Studies Cosmetic Ingredient

Basic Violet 2 NOAEL Studies

INCI: BASIC VIOLET 2

CAS: Verify independently — CI 42520 confirmed (commonly referenced as 3248-91-7)

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

ToxValDB_ECHA_IUCLID 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID LOAEL =50 mg/kg bw/day Rat oral - reproduction developmental QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b8126; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20772/7/9/2?documentUUID=f12588bb-28e0-4f92-a842-d9ad271bee05; YEAR=2010; ORIGINAL_YEAR=2010; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855695_15856463:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_79613a0852cd736ff627ec9dd00c2bc8
ToxValDB_ECHA_IUCLID LOAEL =300 mg/kg bw/day Mouse oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b8122; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20772/7/9/2?documentUUID=f12588bb-28e0-4f92-a842-d9ad271bee05; YEAR=2010; ORIGINAL_YEAR=2010; TOXICOLOGICAL_EFFECT=P0: organ weights and organ / body weight ratios|P0: reproductive function (oestrous cycle); TOXICOLOGICAL_EFFECT_CATEGORY=organ weight|reproduction; STUDY_GROUP=ECHA IUCLID:15856955:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e281f406461ede69d7732d15c0f2d7e1
ToxValDB_ECHA_IUCLID NOAEL =3 mg/kg bw/day Rat oral subchronic; 13 weeks subchronic QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae13e4b0a7c65d1c7728; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20772/7/6/2?documentUUID=f12588bb-28e0-4f92-a842-d9ad271bee05; YEAR=2010; ORIGINAL_YEAR=2010; TOXICOLOGICAL_EFFECT=body weight and weight gain|clinical biochemistry|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical chemistry|organ weight; STUDY_GROUP=ECHA IUCLID:15836852:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d5b7f16574145ebe5c6134954be7694f
ToxValDB_ECHA_IUCLID NOAEL =10 mg/kg bw/day Rat oral - reproduction developmental QUALITY=4 (not assignable); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b8126; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/20772/7/9/2?documentUUID=f12588bb-28e0-4f92-a842-d9ad271bee05; YEAR=2010; ORIGINAL_YEAR=2010; TOXICOLOGICAL_EFFECT=P0: clinical signs|P0: body weight and weight gain|P0: organ weights and organ / body weight ratios|P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|organ weight|reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855695_15856463:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a7d4cead1bdb5241b91c4898d77fb4af