NOAEL Studies Cosmetic Ingredient

Basic Yellow 28 NOAEL Studies

INCI: BASIC YELLOW 28

CAS: 54060-92-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
NTP_ICE_acute_inhalation 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 0.076 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1848; Record_ID=acute_inhalation_1084; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID20879816; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=0.076; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17610/7/3/3/?documentUUID=cdccee09-b5e8-455e-80da-58bc0e30452f; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID20879816
NTP_ICE_acute_inhalation LC50 0.474 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1849; Record_ID=acute_inhalation_1010; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID20879816; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=0.474; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17610/7/3/3/?documentUUID=8c5d2dd0-45e8-456f-b0b0-8f43d7b66fed; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID20879816
NTP_ICE_acute_inhalation LC50 0.29 mg/L - Inhalation Duration=4 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=1850; Record_ID=acute_inhalation_978; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID20879816; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response=0.29; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17610/7/3/3/?documentUUID=8c5d2dd0-45e8-456f-b0b0-8f43d7b66fed; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID20879816
ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =95 mg/kg bw/day Rat oral short-term; 4 weeks short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae65e4b0a7c65d1c8f71; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17610/7/6/2?documentUUID=ff74f945-7780-4ceb-8e9b-cb31ed926ee1; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID:15831948:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_686c652976ca6deb31211a29fc054312
ToxValDB_ECHA_IUCLID NOAEL =300 mg/kg bw/day Rat oral short-term; 14 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cb53e4b0a7c65d225a3f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17610/7/6/2?documentUUID=ff74f945-7780-4ceb-8e9b-cb31ed926ee1; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID:15833012:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a45872da75124adbc79da2c81b1ac146
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =1.12 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15633281:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c8d6a7f21375a126593c362bed0bf12f
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 2HJO358I4S UNII - - - chemical {"approval_status":null,"molecular_formula":"C20H24N3O.CH3O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"2HJO358I4S"}
openFDA substances FDA UNII substance identifier 2HJO358I4S UNII - - - chemical {"approval_status":null,"molecular_formula":"C20H24N3O.CH3O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"2HJO358I4S"}
openFDA substances FDA UNII substance identifier 2HJO358I4S UNII - - - chemical {"approval_status":null,"molecular_formula":"C20H24N3O.CH3O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"2HJO358I4S"}
openFDA substances FDA UNII substance identifier 2HJO358I4S UNII - - - chemical {"approval_status":null,"molecular_formula":"C20H24N3O.CH3O4S","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"2HJO358I4S"}