NOAEL Studies Cosmetic Ingredient

Basic Yellow 57 NOAEL Studies

INCI: BASIC YELLOW 57

CAS: 68391-31-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 100 mg/kg bw/day rat oral 90 day Subchronic SCCS; van Otterdijk, F.M. Repeated dose 90-day oral toxicity study with C 010 by daily gavage in the rat followed by a 28-day recovery period. NOTOX B.V., s’Hertogenbosch,Archive code atHenkel KGaA, Düsseldorf, Report No. R 0500469
SCCNFP Opinion 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =20 mg/kg - dermal Sub-chronic repeated dose toxicity Ref. : 9 2, p.8
SCCNFP Opinion NOAEL =50 mg/kg bw/day rat oral 12 weeks irritation p.19
Regulatory source 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source irritation 50 mg/kg bw/day rat oral 12 weeks irritation p.19
Regulatory source repeated dose toxicity 20 mg/kg - dermal Sub-chronic repeated dose toxicity p.8
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 4N63359G0X UNII - - - chemical -