NOAEL Studies Cosmetic Ingredient

Basic Yellow 87 NOAEL Studies

INCI: BASIC YELLOW 87

CAS: 68259-00-7

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS DB 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS DB LOAEL 50 mg/kg bw/day rat oral 90 day Subchronic SCCS; RCC Project 681311. Subchronic 13-week oral toxicity (feeding) study in the rat
COSMOS DB NOAEL 10 mg/kg bw/day rat oral 90 day Subchronic SCCS; RCC Project 681311. Subchronic 13-week oral toxicity (feeding) study in the rat
SCCNFP Opinion 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCNFP Opinion NOAEL =10 mg/kg bw/day rabbit dermal Sub-chronic repeated dose toxicity p.8
SCCNFP Opinion NOAEL =39 mg/kg bw/day guinea pig dermal - repeated dose toxicity p.6
SCCNFP Opinion NOAEL =60 mg/kg bw human - - dermal absorption p.10
SCCNFP Opinion NOAEL =174 mg/kg bw/day guinea pig dermal - repeated dose toxicity p.6
Regulatory source 6 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source dermal absorption 60 mg/kg bw human - - dermal absorption p.10
Regulatory source repeated dose toxicity 10 mg/kg bw/day rabbit dermal Sub-chronic repeated dose toxicity p.8
Regulatory source repeated dose toxicity 10 mg/kg bw/day rabbit oral subchronic repeated dose toxicity p.18
Regulatory source repeated dose toxicity 39 mg/kg bw/day guinea pig dermal - repeated dose toxicity p.6
Regulatory source repeated dose toxicity 60 mg/kg bw rabbit oral subchronic repeated dose toxicity p.18
Regulatory source repeated dose toxicity 174 mg/kg bw/day guinea pig dermal - repeated dose toxicity p.6
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 224I63D8K4 UNII - - - chemical -