Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Basic Yellow 87. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 10 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| LOAEL | 50 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
Expert Verdict
Phototoxic at concentrations โฅ25% (not at 15%); not photoallergenic; moderately irritating to eyes; some methodological concerns in in vitro genotoxicity with inconclusive chromosomal aberration test; oral LD50 500โ1000 mg/kg in female rats.
Regulatory Flags
Frequently Asked Questions
Is Basic Yellow 87 safe in cosmetics?
Phototoxic at concentrations โฅ25% (not at 15%); not photoallergenic; moderately irritating to eyes; some methodological concerns in in vitro genotoxicity with inconclusive chromosomal aberration test; oral LD50 500โ1000 mg/kg in female rats. The EU classifies Basic Yellow 87 as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Basic Yellow 87 allowed in the EU?
Basic Yellow 87 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Basic Yellow 87 do in cosmetics?
Basic Yellow 87 functions as: Hair dyeing; used at 0.2% in semi-permanent and 0.1% final concentration in oxidative formulations. It is classified as a cosmetic ingredient in our database. CAS number: 68259-00-7.
What is the Margin of Safety for Basic Yellow 87?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Basic Yellow 87?
The NOAEL (No Observed Adverse Effect Level) for Basic Yellow 87 is 10 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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