Also known as: Pyridinium, 1-methyl-4-[(methylphenylhydrazono)methyl]-, methyl sulfate, Pyridinium, 1-methyl-4-[(2-methyl-2-phenylhydrazinylidene)methyl]-, methyl sulfate (1:1), EINECS 269-503-2, UNII-224I63D8K4
INCI: BASIC YELLOW 87
Basic Yellow 87 (CAS 68259-00-7) is a cosmetic cosmetic ingredient functioning as Hair dyeing; used at 0.2% in semi-permanent and 0.1% final concentration in. Reported NOAEL =10 mg/kg bw/day in rabbit (SCCNFP_vision_codex); EU Regulation 1223/2009 status: prohibited; 5 safety opinions reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68259-00-7 →
Basic Yellow 87 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H400, H411).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Basic Yellow 87.
Calculate MoS for your specific formulation with the MoS Calculator.
10 study endpoints found for Basic Yellow 87. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =10 mg/kg bw/day | dermal | rabbit | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =10 mg/kg bw/day | dermal | rabbit | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =10 mg/kg bw/day | dermal | rabbit | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =10 mg/kg bw/day | dermal | rabbit | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =39 mg/kg bw/day | dermal | guinea pig | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =39 mg/kg bw/day | dermal | guinea pig | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =39 mg/kg bw/day | dermal | guinea pig | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =39 mg/kg bw/day | dermal | guinea pig | repeated dose toxicity | SCCNFP_vision_codex |
| NOAEL | =60 mg/kg bw | - | human | dermal absorption | SCCNFP_vision_codex |
| NOAEL | =60 mg/kg bw | - | human | dermal absorption | SCCNFP_vision_codex |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
ata to determine the safety of this ingredient. The Panel concluded that Basic Yellow 87 is safe for use as a hair dye ingredient in the present practices of use and concentration described in this safety assessment. INTRODUCTION Basic Yellow 87 is reported to function as a hair colorant in c
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
1 property record from structured ingredient metadata.
Expert safety assessment and concern-level summary for Basic Yellow 87.
Public NOAEL study rows linked to Basic Yellow 87 by CAS number or substance name.
Units vary across source rows: mg/kg bw/day, mg/kg bw
Basic Yellow 87 has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Basic Yellow 87 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
Basic Yellow 87 functions as: Hair dyeing; used at 0.2% in semi-permanent and 0.1% final concentration in oxidative formulations. It is classified as a cosmetic ingredient in our database. CAS number: 68259-00-7.
The NOAEL (No Observed Adverse Effect Level) for Basic Yellow 87 is =10 mg/kg bw/day based on a repeated dose toxicity study via dermal route in rabbit. A total of 10 study endpoints are available. Source: SCCNFP_vision_codex.
Basic Yellow 87 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Basic Yellow 87 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H400, H411).
Check Basic Yellow 87 compliance across multiple jurisdictions:
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