Bee Propolis

INCI: PROPOLIS EXTRACT

CAS Number
85665-41-4
Function
skin conditioning, antimicrobial, antioxidant, film forming, soothing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Known allergen; patch testing recommended; included in European Standard patch test series; 1.2-6.6% patch test positivity rate

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Bee propolis is a known allergen with moderate to high sensitization potential due to caffeic acid esters and cross-reactivity with fragrance mix; patch testing recommended before use.

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Concern Level: High

Regulatory Flags

allergen sensitizer patch-test-recommended

Frequently Asked Questions

Is Bee Propolis safe in cosmetics?

Bee propolis is a known allergen with moderate to high sensitization potential due to caffeic acid esters and cross-reactivity with fragrance mix; patch testing recommended before use. The EU classifies Bee Propolis as "permitted". Safety rating: MODERATE.

Is Bee Propolis allowed in the EU?

Bee Propolis EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bee Propolis do in cosmetics?

Bee Propolis functions as: skin conditioning, antimicrobial, antioxidant, film forming, soothing. It is classified as a cosmetic ingredient in our database. CAS number: 85665-41-4.

What is the Margin of Safety for Bee Propolis?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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