Good Cosmetic Ingredient NOAEL Data

Behenamidopropyl Dimethylamine

Also known as: EINECS 262-134-8, UNII-X4O854526J

INCI: BEHENAMIDOPROPYL DIMETHYLAMINE

Behenamidopropyl Dimethylamine (CAS 60270-33-9) is a cosmetic cosmetic ingredient functioning as Antistatic, Emulsifier, Hair Conditioning. NOAEL 15 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 60270-33-9 →

Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Emulsifier, Hair Conditioning
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C27H56N2O
MW
424.7 g/mol
EC Number
262-134-8
PubChem CID
108912
IUPAC Name
N-[3-(dimethylamino)propyl]docosanamide
InChIKey
MNAZHGAWPCLLGX-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR 2019: 24 fatty acid amidopropyl dimethylamines safe when formulated to be non-sensitizing.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Behenamidopropyl Dimethylamine.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Behenamidopropyl Dimethylamine. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =5 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex
NOAEL =5 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex
NOAEL =70 mg/kg body weight dermal rabbit repeated dose toxicity CIR_vision_codex
NOAEL =70 mg/kg body weight dermal rabbit repeated dose toxicity CIR_vision_codex
NOAEL =70 mg/kg body weight dermal rabbit repeated dose toxicity CIR_vision_codex
NOAEL =70 mg/kg body weight dermal rabbit repeated dose toxicity CIR_vision_codex
NOAEL =100 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex
NOAEL =100 mg/kg body weight oral rabbit developmental toxicity CIR_vision_codex

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Behenamidopropyl Dimethylamine across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

3 property records from structured ingredient metadata.

emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.32-0.48", "emulsion_stabilization_mechanism": "electrostatic_steric", "co_emulsifier_pairs": "behenyl_alcohol,lactic_acid", "optimal_oil_phase_pct": "12-32", "optimal_water_phase_pct": "68-88", "electrolyte_tolerance": "low", "pH_emulsion_stability_range": "3.0-6.5", "viscosity_building_contribution": …
hair_conditioning
{"cas_number": "60270-33-9", "ingredient_class": "cationic_conditioner", "chemical_type": "quaternary_ammonium", "charge_density_meq_g": "medium", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "no", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic_film_forming", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "long_chain", "…
surfactant
{"cas_number": "60270-33-3", "surfactant_type": "cationic", "chemical_class": "amine_oxide", "charge_at_use_ph": "positive", "cmc_critical_micelle_concentration_mm": "0.03326880704717504", "foam_volume_ml_ross_miles": "54", "foam_quality": "minimal", "foam_stability_5min_pct": "47", "cleansing_power_rating_1_to_10": "4.043788287923578", "oil_emulsification_capacity": "poor", "sebum_removal_efficie…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Emulsifier

Expert Verdict

Expert safety assessment and concern-level summary for Behenamidopropyl Dimethylamine.

Regulatory Flags

ALLERGEN

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Behenamidopropyl Dimethylamine by CAS number or substance name.

Studies
16
Lowest NOAEL
5 mg/kg body weight
Highest NOAEL
200 mg/kg body weight
CIR_vision_codex

Known Synonyms

EINECS 262-134-8 UNII-X4O854526J

Chemical Function

Anti-static agent Emulsifier

Regulatory Lists

Canada; Personal care; Substances in PCP - Canada (4/2014)

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Behenamidopropyl Dimethylamine safe in cosmetics?

Behenamidopropyl Dimethylamine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.

Is Behenamidopropyl Dimethylamine allowed in the EU?

Behenamidopropyl Dimethylamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Behenamidopropyl Dimethylamine do in cosmetics?

Behenamidopropyl Dimethylamine functions as: Antistatic, Emulsifier, Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 60270-33-9.

What is the NOAEL for Behenamidopropyl Dimethylamine?

The NOAEL (No Observed Adverse Effect Level) for Behenamidopropyl Dimethylamine is =5 mg/kg body weight based on a developmental toxicity study via oral route in rabbit. A total of 10 study endpoints are available. Source: CIR_vision_codex.

Is Behenamidopropyl Dimethylamine used outside cosmetics?

Behenamidopropyl Dimethylamine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Behenamidopropyl Dimethylamine have different safety status in cosmetics vs industrial chemicals?

Behenamidopropyl Dimethylamine is classified GHS Danger (H315, H318, H319, H412, H314, H317) in the chemicals database but is allowed in EU cosmetics.

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