NOAEL Studies
Emollient
Behenic Acid NOAEL Studies
INCI: BEHENIC ACID
CAS: 112-85-6
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
NTP_ICE_acute_oral 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | LD50 | >5000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_1229; row=5879; data_type=In Vivo; mixture=Chemical; chemical_name=Docosanoic acid; preferred_name=Docosanoic acid; dtxsid=DTXSID3026930; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3026930; source_file=acute_oral.xlsx |
| NTP_ICE_acute_oral | LD50 | >2000 | mg/kg bw | Rat | oral | acute | Rat Acute Oral Toxicity | record_id=acute_oral_1228; row=5880; data_type=In Vivo; mixture=Chemical; chemical_name=Docosanoic acid; preferred_name=Docosanoic acid; dtxsid=DTXSID3026930; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3026930; source_file=acute_oral.xlsx |
ToxValDB_ECHA_IUCLID 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =1000 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabf4e4b0a7c65d1bca05; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/18930/7/9/3?documentUUID=e491bb11-2f9e-4a7b-8d80-ff69a43669a2; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=maternal: body weight and weight gain|maternal: organ weights and organ / body weight ratios|maternal: pre and post implantation loss|maternal: changes in pregnancy duration|maternal: clinical signs|maternal: dead fetuses|maternal: early or late resorptions|maternal: effects on pregnancy duration|maternal: food consumption and compound intake|maternal: histopathology: non-neoplastic|maternal: mortality|maternal: number of abortions; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|development|food and/or water consumption|mortality/survival|nonneoplastic histopathology|organ weight|reproduction; STUDY_GROUP=ECHA IUCLID:15824431:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_915c4631cbef2cc26134fd33afe20994 |
| ToxValDB_ECHA_IUCLID | NOEL | =1000 | mg/kg bw/day | Rat | oral | subchronic; 63 days | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead96e4b0a7c65d1c4eff; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/18930/7/6/2?documentUUID=e491bb11-2f9e-4a7b-8d80-ff69a43669a2; YEAR=1979; ORIGINAL_YEAR=1979; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837084_15839697_15848259:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_bf691e766f1e8e506232db7865d36ce4 |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =49.3 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15631778:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_b44ad2ea18dbe924fe66af6462522d7e |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | H390488X0A | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C22H44O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H390488X0A"} |
| openFDA substances | FDA UNII substance identifier | H390488X0A | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C22H44O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H390488X0A"} |
| openFDA substances | FDA UNII substance identifier | H390488X0A | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C22H44O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H390488X0A"} |
| openFDA substances | FDA UNII substance identifier | H390488X0A | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C22H44O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H390488X0A"} |