Excellent Emollient NOAEL Data

Behenic Acid

Also known as: EINECS 204-010-8, Glycon B-70, UNII-H390488X0A, 1-Docosanoate, B 95 (+10 more)

INCI: BEHENIC ACID

Behenic Acid (CAS 112-85-6) is a cosmetic emollient functioning as Cleansing, Emulsifier, Opacifier, Surfactant, Smoothing. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.

View industrial chemical safety profile for CAS 112-85-6 →

Auto-generated CPSR Part A draft with source citations

CAS Number

112-85-6

View industrial chemical safety profile →

Function

Cleansing, Emulsifier, Opacifier, Surfactant, Smoothing

Safety Rating

EXCELLENT

Chemistry & Identifiers

Formula

C22H44O2

340.6 g/mol

EC Number

204-010-8

PubChem CID

8215

IUPAC Name

docosanoic acid

InChIKey

UKMSUNONTOPOIO-UHFFFAOYSA-N

ChEBI: CHEBI:28941 UNII: H390488X0A Wikidata: Q422590

Regulatory Status

EU EU Status permitted

US US Status permitted

US Notes CIR: safe when non-irritating/non-sensitizing (2019). FDA GRAS (GRN 69).

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Behenic Acid.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Behenic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint	Value	Route	Species	Study Type	Source
NOAEL	=1000 mg/kg bw/day	oral	Rat	reproduction developmental	ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type

Full

Tonnage Band

1,000 - 10,000 tonnes

Substance Type

SUBSTANCE

SVHC Candidate

Additional Ingredient Properties

5 property records from structured ingredient metadata.

baby_pediatric

{"cas_number": "CAS-FUNC-17", "ingredient_class": "other", "pediatric_safety_rating": "excellent", "minimum_age_months": "0", "neonatal_safe": "yes", "premature_infant_safe": "yes", "skin_barrier_maturity_consideration": "Fatty acid - natural, safe", "transepidermal_absorption_risk_pediatric": "low", "systemic_exposure_concern_pediatric": "low", "dose_per_kg_body_weight_concern": "Functional ingre…

comedogenicity_detail

{"comedogenicity_rating": "1", "irritancy_rating": "0", "skin_type_suitability": "dry,combination,normal", "acne_safe": "yes", "source": "Long-chain fatty acids"}

emulsion_hlb

{"hlb_required_as_emulsifier": "no", "hlb_required_of_oil_phase": "15", "co_emulsifier_pairs": "sodium_hydroxide,triethanolamine", "optimal_oil_phase_pct": "12-32", "optimal_water_phase_pct": "68-88", "droplet_size_range_um": "5-40", "creaming_resistance": "moderate", "coalescence_resistance": "excellent", "ostwald_ripening_resistance": "good", "freeze_thaw_stability": "excellent", "rheology_modif…

hair_conditioning

{"cas_number": "112-85-6", "ingredient_class": "fatty_acid_conditioner", "chemical_type": "fatty_acid", "substantivity_to_hair": "good", "deposition_from_shampoo": "no", "deposition_from_conditioner": "moderate", "conditioning_mechanism": "emollient", "hair_penetration": "surface_only", "molecular_weight_effect_on_penetration": "C22_long_chain", "wet_combing_force_reduction_pct": "25-35", "dry_com…

solubility_hlb

{"water_soluble": "no", "oil_soluble": "yes", "hlb_required": "16.0", "soluble_in": "oils, ethanol", "insoluble_in": "water, glycerin, propylene glycol", "log_p": "10.6", "melting_point_c": "80-82", "appearance": "white powder", "source": "BASF"}

Function Categories & List Membership

Cosmetic/Chemical Function Categories

Cleaning agent Emulsifier Opacifer Surfactant (surface active agent)

Regulatory List Membership (2)

EU Regulated in Personal Care EPA Safer Chemical Ingredients List (SCIL)

Expert Verdict

Expert safety assessment and concern-level summary for Behenic Acid.

Regulatory Flags

epa_safer_alternative

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Behenic Acid by CAS number or substance name.

Studies

Lowest NOAEL

1000 mg/kg bw/day

Highest NOAEL

1000 mg/kg bw/day

ToxValDB_ECHA_IUCLID

Known Synonyms

EINECS 204-010-8 Glycon B-70 UNII-H390488X0A 1-Docosanoate B 95 Behenate CH3-[CH2]20-COOH Docosansaeure Dokosansaeure EXL 5 Heneicosansaeure Hydrofol acid 560 N-Docosanoate docosanic acid docosoic acid

Chemical Function

Surfactant (surface active agent) Emulsifier Cleaning agent Opacifer

Regulatory Lists

inert_ingredient; non_food_use; Pesticides Europe; Personal care Europe; Personal care SCIL (9/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical and food safety data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound

BEHENIC ACID

ChEMBL ID

CHEMBL1173474

View full pharmaceutical profile →

SOURCE EFSA / FDA GRAS fda_gras_enriched

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name

Behenic acid

FDA GRAS

FDA has no questions

GRN

Use in margarine, shortening, and food products that require the use of semi-solid and solid fats as a texturizer at levels up to 8 percent of the oil mass of the food product

View full food safety profile →

Frequently Asked Questions

Is Behenic Acid safe in cosmetics?

Behenic Acid has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Behenic Acid allowed in the EU?

Behenic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Behenic Acid do in cosmetics?

Behenic Acid functions as: Cleansing, Emulsifier, Opacifier, Surfactant, Smoothing. It is classified as a Emollient in our database. CAS number: 112-85-6.

What is the NOAEL for Behenic Acid?

The NOAEL (No Observed Adverse Effect Level) for Behenic Acid is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

Is Behenic Acid used outside cosmetics?

Behenic Acid also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Compliance Tools

Check Behenic Acid compliance across multiple jurisdictions:

Ingredient Decoder

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82 Allergen Checker

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Substance Compliance

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MoS Calculator

Calculate Margin of Safety using SCCS methodology

Heavy Metal Limits

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Solvent

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