Is Behentrimonium Methosulfate safe in cosmetics?
Behentrimonium Methosulfate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Behentrimonium Methosulfate
Also known as: EINECS 279-791-1, UNII-5SHP745C61
INCI: BEHENTRIMONIUM METHOSULFATE
Behentrimonium Methosulfate (CAS 81646-13-1) is a cosmetic cosmetic ingredient functioning as Antistatic, hair conditioning, surfactant, emulsifying. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 81646-13-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Behentrimonium Methosulfate is classified GHS Danger (H315, H318, H319, H373, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic, hair conditioning, surfactant, emulsifying
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
docosyl(trimethyl)azanium;methyl sulfate
InChIKey
QIVLQXGSQSFTIF-UHFFFAOYSA-M
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Allowed - not prohibited or restricted; CIR has reviewed quaternary ammonium compounds broadly
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Behentrimonium Methosulfate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Conditioner | 2–5 | 10 | CIR/VCRP |
Additional Ingredient Properties
6 property records from structured ingredient metadata.
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.20-0.35", "emulsion_stabilization_mechanism": "electrostatic_steric", "co_emulsifier_pairs": "cetearyl_alcohol,cetyl_alcohol", "optimal_oil_phase_pct": "3-10", "optimal_water_phase_pct": "90-97", "electrolyte_tolerance": "low", "pH_emulsion_stability_range": "3.0-7.0", "viscosity_building_contribution"…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "medium/coarse", "curl_pattern_suitability": "curly/coily", "porosity_suitability": "medium/high", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "col…
hair_conditioning
{"cas_number": "81646-13-1", "ingredient_class": "cationic_conditioner", "chemical_type": "quaternary_ammonium", "charge_density_meq_g": "high", "substantivity_to_hair": "excellent", "deposition_from_shampoo": "no", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic_film_forming", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "long_chain_surfa…
sensory
{"silky": "waxy", "smooth, glides easily": "smooth, conditioning", "dry-touch, non-greasy": "soft, detangled", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "1.40": "1.45", "transparent": "opaque", "colorless": "white", "excellent": "fair", "light": "medium", "synthetic": "synthetic"}
synergy
{"inci_name_2": "Cetearyl Alcohol", "synergy_type": "sensory-improvement", "synergy_description": "Cationic emulsifier with fatty alcohol for conditioning emulsions", "combined_benefit": "Enhanced conditioning, improved detangling, elegant texture, stable emulsions", "efficacy_multiplier": "2.3x", "mechanism_of_action": "BTMS provides conditioning and emulsification; cetearyl alcohol adds structur…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": …
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-static agent
Softener and conditioner
Surfactant (surface active agent)
Regulatory List Membership (1)
EU Restricted for Children (Cosmetics)
Expert Verdict
Expert safety assessment and concern-level summary for Behentrimonium Methosulfate.
Regulatory Flags
eu_children_restricted
Known Synonyms
EINECS 279-791-1
UNII-5SHP745C61
Chemical Function
Surfactant (surface active agent)
Anti-static agent
Softener and conditioner
Regulatory Lists
children; Europe; Personal care
children; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Behentrimonium Methosulfate allowed in the EU?
Behentrimonium Methosulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Behentrimonium Methosulfate do in cosmetics?
Behentrimonium Methosulfate functions as: Antistatic, hair conditioning, surfactant, emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 81646-13-1.
Is Behentrimonium Methosulfate used outside cosmetics?
Behentrimonium Methosulfate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Behentrimonium Methosulfate have different safety status in cosmetics vs industrial chemicals?
Behentrimonium Methosulfate is classified GHS Danger (H315, H318, H319, H373, H400, H410, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Behentrimonium Methosulfate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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