NOAEL Studies Cosmetic Ingredient

Beta-Alanine NOAEL Studies

INCI: BETA-ALANINE

CAS: 107-95-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS_DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS_DB NOAEL 3000 mg/kg bw/day rat oral 7 day Short Term Toxicity US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
ToxValDB_ECHA_IUCLID 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaccce4b0a7c65d1c0dbf; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/27826/7/6/2?documentUUID=4a5382a5-b5be-4b57-9b97-ec01aca3db58; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID:15845248:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6707ac8bd8637ce2e16a8c7580a57639
ToxValDB_ECHA_IUCLID NOEL =1000 mg/kg bw/day Rat oral - reproduction developmental QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eabb9e4b0a7c65d1bb6eb; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/27826/7/9/3?documentUUID=4a5382a5-b5be-4b57-9b97-ec01aca3db58; YEAR=1993; ORIGINAL_YEAR=1993; STUDY_GROUP=ECHA IUCLID:15822944:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_a525b45d1b99bb0316e163296311abd6
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =23.509 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629507:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_bf9902b6334615b3d8d526ccc62dd1cb
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 11P2JDE17B UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H7NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"11P2JDE17B"}
openFDA substances FDA UNII substance identifier 11P2JDE17B UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H7NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"11P2JDE17B"}
openFDA substances FDA UNII substance identifier 11P2JDE17B UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H7NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"11P2JDE17B"}
openFDA substances FDA UNII substance identifier 11P2JDE17B UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H7NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"11P2JDE17B"}