Regulatory Status
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Safety Data
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Expert Verdict
Highest concern ingredient. Low molecular weight (~204 Da) enables dermal penetration. Primary amine groups are reactive with potential for skin sensitization and cross-reactivity. Full toxicology dossier required including dermal absorption (OECD 428), sensitization (LLNA), mutagenicity (Ames), and 90-day repeat dose studies. Use concentration must be tightly controlled.
Regulatory Flags
Frequently Asked Questions
Is Bis-Aminopropyl Diglycol safe in cosmetics?
Highest concern ingredient. Low molecular weight (~204 Da) enables dermal penetration. Primary amine groups are reactive with potential for skin sensitization and cross-reactivity. Full toxicology dossier required including dermal absorption (OECD 428), sensitization (LLNA), mutagenicity (Ames), and 90-day repeat dose studies. Use concentration must be tightly controlled. The EU classifies Bis-Aminopropyl Diglycol as "prohibited". Safety rating: MODERATE.
Is Bis-Aminopropyl Diglycol allowed in the EU?
Bis-Aminopropyl Diglycol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Bis-Aminopropyl Diglycol do in cosmetics?
Bis-Aminopropyl Diglycol functions as: Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: | Tier 3 — Moderate Risk.
What is the Margin of Safety for Bis-Aminopropyl Diglycol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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