Bis-HEMA PPG-12/HDI Copolymer

INCI: BIS-HEMA PPG-12/HDI COPOLYMER

CAS Number
Not publicly assigned
Function
Nail conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA. CIR reviewed HDI polymers separately (2016) โ€” 17 HDI polymers found safe as used; 2 were data-insufficient. This specific ingredient may fall under insufficient data depending on MW documentation.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

HDI-based polymer with adequate safety profile when MW is documented above 1000 Da; residual HDI monomer must be below 20 ppm to ensure adequate margin of safety, as free HDI is a potent respiratory and contact sensitizer.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Bis-HEMA PPG-12/HDI Copolymer safe in cosmetics?

HDI-based polymer with adequate safety profile when MW is documented above 1000 Da; residual HDI monomer must be below 20 ppm to ensure adequate margin of safety, as free HDI is a potent respiratory and contact sensitizer. The EU classifies Bis-HEMA PPG-12/HDI Copolymer as "permitted". Safety rating: GOOD.

Is Bis-HEMA PPG-12/HDI Copolymer allowed in the EU?

Bis-HEMA PPG-12/HDI Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bis-HEMA PPG-12/HDI Copolymer do in cosmetics?

Bis-HEMA PPG-12/HDI Copolymer functions as: Nail conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.

What is the Margin of Safety for Bis-HEMA PPG-12/HDI Copolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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