NOAEL Studies Active Ingredient

Boric Acid NOAEL Studies

INCI: BORIC ACID

CAS: 11113-50-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

Back to parent ingredient page
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =55 mg/kg bw/day Rat - 20 days reproduction toxicity EFSA ANS - 2013 - OutputID 2370 - development - teratogenic - Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives. - doi:10.2903/j.efsa.2013.3407
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =9.6 mg/kg bw/day Rat oral: feed 21 days reproduction toxicity EFSA AFC - 2006 - OutputID 377 - body weight - teratogenic - Statement of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission related to Boric Acid and Sodium borate as nutrient sources of boron. - doi:10.2903/j.efsa.2005.1044
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =55 mg/kg bw/day Rat - 20 days reproduction toxicity EFSA ANS - 2013 - OutputID 2370 - development - teratogenic - Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives. - doi:10.2903/j.efsa.2013.3407
EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx NOAEL =9.6 mg/kg bw/day Rat oral: feed 21 days reproduction toxicity EFSA AFC - 2006 - OutputID 377 - body weight - teratogenic - Statement of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission related to Boric Acid and Sodium borate as nutrient sources of boron. - doi:10.2903/j.efsa.2005.1044
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ADI =0.16 mg/kg bw/day Consumers - - ADI EFSA ANS - 2013 - OutputID 2370 - Consumers - Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives. - doi:10.2903/j.efsa.2013.3407
EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx ADI =0.16 mg/kg bw/day Consumers - - ADI EFSA ANS - 2013 - OutputID 2370 - Consumers - Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives. - doi:10.2903/j.efsa.2013.3407
ToxValDB_EFSA 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_EFSA NOAEL =55 mg/kg bw/day Rat oral short-term; 20 days developmental LONG_REF=EFSA ANS (2013). Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives. doi:10.2903/j.efsa.2013.3407.; TITLE=Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives.; AUTHOR=EFSA ANS; DOI=doi:10.2903/j.efsa.2013.3407; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/65201d30e4b0f0a60ddd1165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://zenodo.org/record/5076033#.Y9fEoXbMI2z; YEAR=2013; ORIGINAL_YEAR=2013; TOXICOLOGICAL_EFFECT=development; TOXICOLOGICAL_EFFECT_CATEGORY=development; STUDY_GROUP=EFSA:15614314:F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7b6e6e57bafa00ef258e7c2418ea8842
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier R57ZHV85D4 UNII - - - chemical {"approval_status":null,"molecular_formula":"BH3O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"R57ZHV85D4"}
openFDA substances FDA UNII substance identifier R57ZHV85D4 UNII - - - chemical {"approval_status":null,"molecular_formula":"BH3O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"R57ZHV85D4"}
openFDA substances FDA UNII substance identifier R57ZHV85D4 UNII - - - chemical {"approval_status":null,"molecular_formula":"BH3O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"R57ZHV85D4"}
openFDA substances FDA UNII substance identifier R57ZHV85D4 UNII - - - chemical {"approval_status":null,"molecular_formula":"BH3O3","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"R57ZHV85D4"}