Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Bruceine is a quassinoid compound derived from Brucea javanica with anti-inflammatory, anti-malarial, and antiviral activity, primarily used in pharmaceutical and research contexts. Safety at cosmetic use concentrations is not fully established, and it has very limited documented cosmetic use. Caution is advised.
Regulatory Flags
Frequently Asked Questions
Is Bruceine safe in cosmetics?
Bruceine is a quassinoid compound derived from Brucea javanica with anti-inflammatory, anti-malarial, and antiviral activity, primarily used in pharmaceutical and research contexts. Safety at cosmetic use concentrations is not fully established, and it has very limited documented cosmetic use. Caution is advised. The EU classifies Bruceine as "permitted". Safety rating: MODERATE.
Is Bruceine allowed in the EU?
Bruceine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bruceine do in cosmetics?
Bruceine functions as: Antimicrobial, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 25514-31-2.
What is the Margin of Safety for Bruceine?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Bruceine compliance across multiple jurisdictions:
Related Ingredients
Is Bruceine in Your Products?
Scan any product label with Piro โ our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free โAnalyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Bruceine in your formulation.