Is Bruceine safe in cosmetics?
Bruceine has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Bruceine
INCI: BRUCEINE
Bruceine (CAS 25514-31-2) is a cosmetic cosmetic ingredient functioning as Antimicrobial, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 25514-31-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
methyl (1R,2S,3R,6R,8R,13S,14R,15R,16S,17S)-10,15,16-trihydroxy-9,13-dimethyl-3-(3-methylbutanoyloxy)-4,11-dioxo-5,18-dioxapentacyclo[12.5.0.01,6.02,17.08,13]nonadec-9-ene-17-carboxylate
InChIKey
LPZSTPCYWWRQFU-VILODJCFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA cosmetic restriction; primarily a research/pharmaceutical compound with very limited cosmetic use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Bruceine.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Bruceine.
Regulatory Flags
pharmaceutical_compound
data_gap
cytotoxic_high_dose
verify_inci_name
Frequently Asked Questions
Is Bruceine allowed in the EU?
Bruceine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Bruceine do in cosmetics?
Bruceine functions as: Antimicrobial, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 25514-31-2.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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