NOAEL Studies Cosmetic Ingredient

Calcium Oxide NOAEL Studies

INCI: CALCIUM OXIDE

CAS: 1305-78-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS_DB 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS_DB NOAEL 440 mg/kg bw/day mouse oral 10 day Developmental US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
COSMOS_DB NOAEL 680 mg/kg bw/day rat oral 10 day Developmental US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
NTP_ICE_eye_irritation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_eye_irritation GHS Classification 1 unitless Rabbit Ocular - In Vivo; Draize Eye Irritation/Corrosion Test sheet=Data; excel_row=1607; Record_ID=eye_irritation_114; Data_Type=In Vivo; Mixture=Chemical; DTXSID=DTXSID5029631; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=GHS Classification; Response=1; Response_Unit=Unitless; Species=Rabbit; Reference=ICCVAM 2006; URL=https://ntp.niehs.nih.gov/sites/default/files/iccvam/docs/ocutox_docs/oteval/otevalrpt.pdf; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID5029631
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL local =1 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15630558:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_de45d9c631611d4421a2a7cd8f8948af
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier C7X2M0VVNH UNII - - - chemical {"approval_status":null,"molecular_formula":"Ca.O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C7X2M0VVNH"}
openFDA substances FDA UNII substance identifier C7X2M0VVNH UNII - - - chemical {"approval_status":null,"molecular_formula":"Ca.O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C7X2M0VVNH"}
openFDA substances FDA UNII substance identifier C7X2M0VVNH UNII - - - chemical {"approval_status":null,"molecular_formula":"Ca.O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C7X2M0VVNH"}
openFDA substances FDA UNII substance identifier C7X2M0VVNH UNII - - - chemical {"approval_status":null,"molecular_formula":"Ca.O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"C7X2M0VVNH"}