Good Cosmetic Ingredient

Calcium Sodium Fluorophosphosilicate

INCI: CALCIUM SODIUM FLUOROPHOSPHOSILICATE

CAS Number
Not well-established (bioactive glass variant; no single CAS universally assigned — check supplier CoA)
Function
Oral Care (enamel remineralization, fluoride delivery)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 0.15%
🇺🇸 US Status permitted
US Notes Conditional — MoS dependent on total fluoride exposure calculation per product. Fluoride-containing oral products are OTC drugs, not cosmetics — dual classification issues. Ensure total F concentration from all sources stays ≤0.15% (EU) or per FDA monograph limits.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Fluoride content triggers EU Annex III compliance; restricted to 0.15% maximum. In the US, fluoride-containing oral products may be classified as OTC drugs rather than cosmetics, requiring careful compliance with both regulatory frameworks and total fluoride concentration limits from all sources.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Calcium Sodium Fluorophosphosilicate safe in cosmetics?

Fluoride content triggers EU Annex III compliance; restricted to 0.15% maximum. In the US, fluoride-containing oral products may be classified as OTC drugs rather than cosmetics, requiring careful compliance with both regulatory frameworks and total fluoride concentration limits from all sources. The EU classifies Calcium Sodium Fluorophosphosilicate as "restricted". Safety rating: GOOD.

Is Calcium Sodium Fluorophosphosilicate allowed in the EU?

Calcium Sodium Fluorophosphosilicate EU regulatory status: restricted. Maximum allowed concentration: 0.15%. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Sodium Fluorophosphosilicate do in cosmetics?

Calcium Sodium Fluorophosphosilicate functions as: Oral Care (enamel remineralization, fluoride delivery). It is classified as a cosmetic ingredient in our database. CAS number: Not well-established (bioactive glass variant; no single CAS universally assigned — check supplier CoA).

What is the Margin of Safety for Calcium Sodium Fluorophosphosilicate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Calcium Sodium Fluorophosphosilicate compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Glycerophosphoinositol Arginine
Moderate
Dimethyl Stearamine
Good
Acrylates/Methoxy PEG-90 Methacrylate Crosspolymer
Good
Glycol/Butylene Glycol Hydroxyphenylpropamidobenzoate
Good
Resorcinol Dipentyl Ether
Moderate
Browse all 30,000+ ingredients →
📱

Is Calcium Sodium Fluorophosphosilicate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Calcium Sodium Fluorophosphosilicate in your formulation.

Ingredient Decoder MoS Calculator