Good Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

Calcium Stearoyl Lactylate

INCI: CALCIUM STEAROYL LACTYLATE

CAS Number
5793-94-2
Function
Surfactant — Cleansing; Surfactant — Emulsifying (W/O emulsifier)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Safety

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Calcium Stearoyl Lactylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 12500 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 12500 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 12500 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 2500 mg/kg bw/day oral rat Multigeneration Reproductive COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 16000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 25000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 7500 mg/kg bw/day oral dog Short Term Toxicity COSMOS_DB
NOAEL 5000 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe
NOAEL: 2200 mg/kg body weight/day (oral)

redients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted method

cir
Verdict: safe
NOAEL: 2214 mg/kg/day (oral)

redients, and concluded that these 10 ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment when formulated to be nonirritating and nonsensitizing, which may be based on a quantitative risk assessment (QRA) or other accepted method

Expert Verdict

Origin may be animal-derived (tallow stearic acid) or synthetic; document source for vegan/halal/COSMOS claims. Superior moisturizing properties and excellent functional profile for lip care and styling products.

⚠️
Concern Level: Low

Regulatory Flags

fda_food_additive

Frequently Asked Questions

Is Calcium Stearoyl Lactylate safe in cosmetics?

Origin may be animal-derived (tallow stearic acid) or synthetic; document source for vegan/halal/COSMOS claims. Superior moisturizing properties and excellent functional profile for lip care and styling products. The EU classifies Calcium Stearoyl Lactylate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Calcium Stearoyl Lactylate allowed in the EU?

Calcium Stearoyl Lactylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calcium Stearoyl Lactylate do in cosmetics?

Calcium Stearoyl Lactylate functions as: Surfactant — Cleansing; Surfactant — Emulsifying (W/O emulsifier). It is classified as a cosmetic ingredient in our database. CAS number: 5793-94-2.

What is the Margin of Safety for Calcium Stearoyl Lactylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Calcium Stearoyl Lactylate?

The NOAEL (No Observed Adverse Effect Level) for Calcium Stearoyl Lactylate is 12500 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

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