Regulatory Status
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Safety Data
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Expert Verdict
CIR Expert Panel (2025) found insufficient data to determine safety for Carica Papaya Leaf Extract in cosmetic formulations, contrasting with fruit-derived papaya ingredients which were cleared as safe. Not prohibited or restricted under EU Cosmetics Regulation 1223/2009; permitted in US cosmetics. Key concerns include inadequate toxicological dataset, potential latex cross-reactivity for sensitized individuals, and tannin-related irritation potential at high concentrations.
Regulatory Flags
Frequently Asked Questions
Is Carica Papaya Leaf Extract safe in cosmetics?
CIR Expert Panel (2025) found insufficient data to determine safety for Carica Papaya Leaf Extract in cosmetic formulations, contrasting with fruit-derived papaya ingredients which were cleared as safe. Not prohibited or restricted under EU Cosmetics Regulation 1223/2009; permitted in US cosmetics. Key concerns include inadequate toxicological dataset, potential latex cross-reactivity for sensitized individuals, and tannin-related irritation potential at high concentrations. The EU classifies Carica Papaya Leaf Extract as "permitted". Safety rating: MODERATE.
Is Carica Papaya Leaf Extract allowed in the EU?
Carica Papaya Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Carica Papaya Leaf Extract do in cosmetics?
Carica Papaya Leaf Extract functions as: Skin conditioning agent (tonic); antioxidant; supports skin barrier; photoprotective activity via suppression of UVB-induced MMP activation and ROS scavenging. It is classified as a cosmetic ingredient in our database. CAS number: 84012-30-6.
What is the Margin of Safety for Carica Papaya Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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