Moderate Cosmetic Ingredient NOAEL Data

Ceteareth-100

INCI: CETEARETH-100

CAS Number
68439-49-6
Function
Surfactant (cleansing agent)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; CIR: safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Ceteareth-100. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 800 mg/kg bw/day oral rat oral REACH
NOAEL 800 mg/kg bw/day oral rat oral REACH

Expert Verdict

Surfactant with 1,4-dioxane impurity concern; avoid use on damaged skin.

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Concern Level: Moderate

Regulatory Flags

eu_children_restricted epa_safer_alternative

Frequently Asked Questions

Is Ceteareth-100 safe in cosmetics?

Surfactant with 1,4-dioxane impurity concern; avoid use on damaged skin. The EU classifies Ceteareth-100 as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Ceteareth-100 allowed in the EU?

Ceteareth-100 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ceteareth-100 do in cosmetics?

Ceteareth-100 functions as: Surfactant (cleansing agent). It is classified as a cosmetic ingredient in our database. CAS number: 68439-49-6.

What is the Margin of Safety for Ceteareth-100?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ceteareth-100?

The NOAEL (No Observed Adverse Effect Level) for Ceteareth-100 is 800 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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