Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Ceteareth-12. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 800 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 800 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Surfactant with potential 1,4-dioxane impurities; use with caution on damaged skin due to penetration enhancement properties.
Regulatory Flags
Frequently Asked Questions
Is Ceteareth-12 safe in cosmetics?
Surfactant with potential 1,4-dioxane impurities; use with caution on damaged skin due to penetration enhancement properties. The EU classifies Ceteareth-12 as "restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Ceteareth-12 allowed in the EU?
Ceteareth-12 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ceteareth-12 do in cosmetics?
Ceteareth-12 functions as: Surfactant (emulsifying agent). It is classified as a cosmetic ingredient in our database. CAS number: 68439-49-6.
What is the Margin of Safety for Ceteareth-12?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ceteareth-12?
The NOAEL (No Observed Adverse Effect Level) for Ceteareth-12 is 800 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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