Moderate Cosmetic Ingredient NOAEL Data

Cetearyl Phosphate

INCI: CETEARYL PHOSPHATE

CAS Number
90506-73-3
Function
Skin conditioning, emulsifying
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; phosphate esters used broadly in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Cetearyl Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
BMDL10 240.3 mg/kg bw/day oral rat oral REACH
NOEL 227 mg/kg bw/day oral rat oral REACH

Expert Verdict

Limited safety data available; supplier safety dossier recommended. Monitor formulation pH as phosphate esters can alter pH.

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Concern Level: Moderate

Frequently Asked Questions

Is Cetearyl Phosphate safe in cosmetics?

Limited safety data available; supplier safety dossier recommended. Monitor formulation pH as phosphate esters can alter pH. The EU classifies Cetearyl Phosphate as "permitted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.

Is Cetearyl Phosphate allowed in the EU?

Cetearyl Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetearyl Phosphate do in cosmetics?

Cetearyl Phosphate functions as: Skin conditioning, emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 90506-73-3.

What is the Margin of Safety for Cetearyl Phosphate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Cetearyl Phosphate?

The NOAEL (No Observed Adverse Effect Level) for Cetearyl Phosphate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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