Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Cetoleth-25. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Surfactant with potential residual contaminants (1,4-dioxane and ethylene oxide) requiring appropriate manufacturing controls.
Frequently Asked Questions
Is Cetoleth-25 safe in cosmetics?
Surfactant with potential residual contaminants (1,4-dioxane and ethylene oxide) requiring appropriate manufacturing controls. The EU classifies Cetoleth-25 as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is Cetoleth-25 allowed in the EU?
Cetoleth-25 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cetoleth-25 do in cosmetics?
Cetoleth-25 functions as: Surfactant — emulsifying, cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 68920-66-1.
What is the Margin of Safety for Cetoleth-25?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Cetoleth-25?
The NOAEL (No Observed Adverse Effect Level) for Cetoleth-25 is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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