NOAEL Studies
Cosmetic Ingredient
Cetyl Betaine NOAEL Studies
INCI: CETYL BETAINE
CAS: 693-33-4
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ToxValDB_ECHA_IUCLID 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | >250 | mg/kg bw/day | Rat | oral | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac7be4b0a7c65d1bf4c2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/23579/7/9/3?documentUUID=5c6d1924-6cb5-40be-ae9f-50b1b7e4e74d; YEAR=2017; ORIGINAL_YEAR=2017; TOXICOLOGICAL_EFFECT=fetus: skeletal malformations; TOXICOLOGICAL_EFFECT_CATEGORY=development; STUDY_GROUP=ECHA IUCLID:15821542:M/F:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_609db83fb4cb915c8e4b5bf54a9530c2 |
| ToxValDB_ECHA_IUCLID | NOAEL | <50 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac7be4b0a7c65d1bf4c2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/23579/7/9/3?documentUUID=5c6d1924-6cb5-40be-ae9f-50b1b7e4e74d; YEAR=2017; ORIGINAL_YEAR=2017; TOXICOLOGICAL_EFFECT=maternal: body weight and weight gain|maternal: clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs; STUDY_GROUP=ECHA IUCLID:15822844:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_8d66661568013f33ecc8a0b94082a6de |
| ToxValDB_ECHA_IUCLID | NOAEL | =350 | mg/kg bw/day | Rat | oral | - | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaeb0e4b0a7c65d1ca6d4; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/22986/7/6/2?documentUUID=fdb90070-9a95-40e7-a78c-21e16e3444dd; YEAR=2017; ORIGINAL_YEAR=2017; TOXICOLOGICAL_EFFECT=clinical signs; TOXICOLOGICAL_EFFECT_CATEGORY=clinical signs; STUDY_GROUP=ECHA IUCLID:15844323:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ab5cddae2cc96cc394e278e0a24cae58 |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | E945X08YA9 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H41NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E945X08YA9"} |
| openFDA substances | FDA UNII substance identifier | E945X08YA9 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H41NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E945X08YA9"} |
| openFDA substances | FDA UNII substance identifier | E945X08YA9 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H41NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E945X08YA9"} |
| openFDA substances | FDA UNII substance identifier | E945X08YA9 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C20H41NO2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"E945X08YA9"} |